Gene family: endogenous retroviral sequences; (ERV1 ERV3 ERVF1 ERVF2 ERVF3 ERVT1 ERVT2 ERVT3 ERVT4 ERVT5 ERVH1 ERVH2 ERVPL1 ERVPL2 ERVK1 ERVK2 ERVK3 ERVNP2 ERVSSA ERVSSAL)

SUM

The endogenous retroviral sequences (ERV) are an integral part of the human genome. Presumably, at some time during the course of human evolution, exogenous progenitors of ERVs inserted themselves into the cells of the germ line, where they have been replicated along with the host's cellular genes. Furthermore, due to their unique genomic structure, ERVs have been subjected to many amplification and transposition events, resulting in a widespread distribution of complete or partial retroviral sequences throughout the human genome. ERV sequences comprise about 1% of the human genome."

REF

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