Gene family: protein phosphatase polypeptides and pseudogenes; (PPP1CA PPP1CB PPP1CC PPP1R1A PPP1R1B PPP1R2 PPP1R2P PPP1R3 PPP1R5 PPP1R6 PPP1R7 PPP1R8 PPP1R8P PPP2CA PPP2CB PPP2CBP PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3 PPP2R4 PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PPP4C PPP5C PPP6C PPM1A PPM1B PPM1G PPM2C)

FUN

Protein phosphatase-1 (PP1) participates in the regulation of a wide variety of cellular functions by reversible protein phosphorylation. The ability of PP1 to regulate diverse functions resides in its capacity to interact with a variety of regulatory subunits that may target PP1 to specific subcellular locations, modulate its substrate specificity, and allow its activity to be responsive to extracellular signals. Several targeting subunits of PP1 have been identified, including the glycogen-binding subunits PPP1R3 (GEM:00.0/PPP1R3) and PPP1R4, and the nuclear inhibitor of PP1 (GEM:00.0/PPP1R8)."