Gene superfamily: protein tyrosine kinases; (MLK1 MLK2 MLK3 PTK2 PTK3A PTK3B PTK4 PTK5 PTK6 PTK7 PTK8 PTK9 TEC TXK)


SUM

Protein tyrosine kinases (PTKs) are involved in the regulation of tyrosine phosphorylation-mediated signaling. Such signaling is critical for the regulation of cell proliferation, differentiation, and neoplastic transformation. Tyrosine-phosphorylated proteins can be specifically dephosphorylated through the action of protein tyrosine phosphatases, see FAM:PTP/00.0."