Рис. 11 pat
Нуклеотидная и аминокислотная последовательности гена OCA-2 человека.
cactcctggagaaagatctgcaagtgcgcagagagaagactggcagtggagc
atg cat ctg gag ggc aga gac ggc agg cgg tac ccc ggc gcg ccg
met his leu glu gly arg asp gly arg arg tyr pro gly ala pro 15
gcg gtg gag ctc ctg cag acg tcc gtg ccc agc gga ctc gct gaa
ala val glu leu leu gln thr ser val pro ser gly leu ala glu 30
ctt gtg gcc ggc aag cgc agg ctt cct cgg gga gcc ggt gga gct
leu val ala gly lys arg arg leu pro arg gly ala gly gly ala 45
gac ccc tcg cac tcc tgc ccc agg ggg gct gcc ggg cag agc tct
asp pro ser his ser cys pro arg gly ala ala gly gln ser ser 60
tgg gct cct gca ggc cag gag ttt gct tca ttc ctc aca aaa ggg
trp ala pro ala gly gln glu phe ala ser phe leu thr lys gly 75
agg tct cac tct tct ttg ccc cag atg tcc agc tcc agg tct aaa
arg ser his ser ser leu pro gln met ser ser ser arg ser lys 90
gat tcc tgc ttt aca gaa aac act cct ttg ctg agg aat tcc tta
asp ser cys phe thr glu asn thr pro leu leu arg asn ser leu 105
cag gag aaa ggg tca cgg tgc ata cct gtt tac cat cca gag ttc
gln glu lys gly ser arg cys ile pro val tyr his pro glu phe 120
atc act gct gaa gag tct tgg gaa gac agc tct gct gac tgg gag
ile thr ala glu glu ser trp glu asp ser ser ala asp trp glu 135
cga aga tac ctg cta agc agg gag gtg tct ggt ctg tct gca tct
arg arg tyr leu leu ser arg glu val ser gly leu ser ala ser 150
gcc tcc tcc gag aag gga gac ctt ctg gac agc ccg cac atc cga
ala ser ser glu lys gly asp leu leu asp ser pro his ile arg 165
ctc cgt ctt tcc aag ctg agg cgc tgt gtg cag tgg ctg aaa gtc
leu arg leu ser lys leu arg arg cys val gln trp leu lys val 180
atg ggc ctg ttt gcc ttt gtg gtg ctg tgt tct att ttg ttc agc
met gly leu phe ala phe val val leu cys ser ile leu phe ser 195
cta tat ccg gat caa gga aag ctc tgg cag ctg ttg gcc tta tca
leu tyr pro asp gln gly lys leu trp gln leu leu ala leu ser 210
ccg ctg gag aac tac tcc gtg aac ctt agc agc cac gtg gac tcc
pro leu glu asn tyr ser val asn leu ser ser his val asp ser 225
acg ctg ctg cag gtg gac ctg gca ggg gcc cta gtg gcc agt ggg
thr leu leu gln val asp leu ala gly ala leu val ala ser gly 240
ccg agt cgt cct ggg agg gaa gag cac atc gtg gtg gag ctg acc
pro ser arg pro gly arg glu glu his ile val val glu leu thr 255
cag gat gac gct ttg ggc tcc agg tgg cgg cgg cca cag cag gtc
gln asp asp ala leu gly ser arg trp arg arg pro gln gln val 270
act cac aac tgg acg gtg tat tta aat ccg agg aga agc gag cac
thr his asn trp thr val tyr leu asn pro arg arg ser glu his 285
tca gtg atg agc agg acc ttt gag gta ctg acc aga gag acg gtg
ser val met ser arg thr phe glu val leu thr arg glu thr val 300
tcc atc agc atc cgg gcc tcc ctg cag cag acc cag gct gtc cct
ser ile ser ile arg ala ser leu gln gln thr gln ala val pro 315
ctt ttg atg gct cat cag tac ctc cgc gga agt gta gaa acc cag
leu leu met ala his gln tyr leu arg gly ser val glu thr gln 330
gtg acc atc gcg acg gcc atc ctc gcg ggc gtc tac gcg ctg atc
val thr ile ala thr ala ile leu ala gly val tyr ala leu ile 345
ata ttt gag atc gtg cac aga act ctg gcg gcc atg ctg ggt tcc
ile phe glu ile val his arg thr leu ala ala met leu gly ser 360
ctt gca gca ctg gca gca ctg gct gtg att ggc gat aga ccc agc
leu ala ala leu ala ala leu ala val ile gly asp arg pro ser 375
ctg acc cat gtg gtg gag tgg att gat ttt gag acg ctg gcc ctg
leu thr his val val glu trp ile asp phe glu thr leu ala leu 390
ctg ttt ggc atg atg atc tta gta gcc ata ttt tca gaa acg gga
leu phe gly met met ile leu val ala ile phe ser glu thr gly 405
ttt ttc gat tat tgt gct gta aag gca tac cgg ctc tcc cgg gga
phe phe asp tyr cys ala val lys ala tyr arg leu ser arg gly 420
cgg gtg tgg gcc atg atc atc atg ctc tgt ctc atc gcg gcc gtc
arg val trp ala met ile ile met leu cys leu ile ala ala val 435
ctc tct gcc ttc ttg gac aac gtc acc acc atg ctc ctc ttc acg
leu ser ala phe leu asp asn val thr thr met leu leu phe thr 450
cct gtg acc ata agg ttg tgt gag gtg ctc aac ctt gat cca aga
pro val thr ile arg leu cys glu val leu asn leu asp pro arg 465
caa gtc ctg att gca gaa gtg atc ttc aca aac att gga gga gct
gln val leu ile ala glu val ile phe thr asn ile gly gly ala 480
gcc act gcc atc ggg gac cct cca aat gtc att att gtt tcc aac
ala thr ala ile gly asp pro pro asn val ile ile val ser asn 495
caa gag ctg agg aag atg ggc ctg gac ttt gcc gga ttc act gca
gln glu leu arg lys met gly leu asp phe ala gly phe thr ala 510
cac atg ttc att ggg att tgc ctt gtt ctc ctg gtc tgc ttt ccg
his met phe ile gly ile cys leu val leu leu val cys phe pro 525
ctc ctc aga ctc ctt tac tgg aac aga aag ctt tat aac aag gaa
leu leu arg leu leu tyr trp asn arg lys leu tyr asn lys glu 540
ccc agt gag att gtt gaa ctg aag cac gag att cac gtc tgg cgc
pro ser glu ile val glu leu lys his glu ile his val trp arg 555
ctg act gct cag cgc atc agc ccg gcc agc cgc gag gag aca gct
leu thr ala gln arg ile ser pro ala ser arg glu glu thr ala 570
gtg cgc cgc ctg ctg ctg ggg aag gtg ctg gca ctg gag cac ctg
val arg arg leu leu leu gly lys val leu ala leu glu his leu 585
ctc gcc cgg agg ctg cac acc ttc cac aga cag atc tca cag gag
leu ala arg arg leu his thr phe his arg gln ile ser gln glu 600
gac aaa aat tgg gag acc aat atc caa gaa ctc caa aaa aag cat
asp lys asn trp glu thr asn ile gln glu leu gln lys lys his 615
agg ata tct gac ggg att ctg ctc gcc aaa tgc ctg aca gtg ttg
arg ile ser asp gly ile leu leu ala lys cys leu thr val leu 630
gga ttt gtt atc ttc atg ttt ttc ctc aat tcg ttt gtc cct ggc
gly phe val ile phe met phe phe leu asn ser phe val pro gly 645
att cat ctt gat ctt gga tgg att gct att ctg ggt gcc atc tgg
ile his leu asp leu gly trp ile ala ile leu gly ala ile trp 660
ttg cta att tta gct gat att cat gat ttt gag ata att cta cac
leu leu ile leu ala asp ile his asp phe glu ile ile leu his 675
aga gtg gaa tgg gca acc ctt ctg ttt ttt gca gcg ctc ttt gtt
arg val glu trp ala thr leu leu phe phe ala ala leu phe val 690
ctg atg gag gca ttg gca cat ctc cac tta ata gaa tat gtt gga
leu met glu ala leu ala his leu his leu ile glu tyr val gly 705
gaa caa act gct ttg cta ata aag atg gtc cca gag gag cag cgc
glu gln thr ala leu leu ile lys met val pro glu glu gln arg 720
ctc ata gcc gcc att gtc ctg gtg gtg tgg gtc tca gcc ctg gcg
leu ile ala ala ile val leu val val trp val ser ala leu ala 735
tcg tcc ctg att gac aac atc ccg ttc act gct acc atg att ccc
ser ser leu ile asp asn ile pro phe thr ala thr met ile pro 750
gtg ctc ctg aac ctg agc cac gac cct gag gtt ggc ctg ccc gca
val leu leu asn leu ser his asp pro glu val gly leu pro ala 765
ccg ccg ctc atg tat gcc ctg gcc ttc ggt gct tgc ctg gga ggc
pro pro leu met tyr ala leu ala phe gly ala cys leu gly gly 780
aac ggg aca ctg att ggc gcg tcg gca aac gtc gtg tgt gca ggg
asn gly thr leu ile gly ala ser ala asn val val cys ala gly 795
att gca gaa cag cat gga tat ggg ttc tcc ttc atg gaa ttt ttc
ile ala glu gln his gly tyr gly phe ser phe met glu phe phe 810
agg ctg ggc ttc cca atg atg gtt gtg tcc tgc act gtt ggg atg
arg leu gly phe pro met met val val ser cys thr val gly met 825
tgt tat ctc ctt gtg gct cat gtg gtg gtg gga tgg aat taa tag
cys tyr leu leu val ala his val val val gly trp asn ter
acatccatctattgctcgaagactaaaggaaacttcatccatcacaacccattagtca
taaaactaccctgaccccactgtttgaagaagaaaaggtgcttaccctggagatgcta
cagagacacagtggaatagaccttgacactaacactctaattcaagcgaatgttggaa
caccatgacctcctctgtgtgtcctttctccccaaggacaaaatgtagaaagatgtga
gataacttactcaagattcccctccagaaaaatacgtatgtttaaaaacccttcctgc
tatacataggaaaagacacacatccacctaaaattgactgtactgtttaactgtcaat
tctcctgaggctaaacacagtttgtttttcttgtaatcacttttcatgttaaaataat
cagcattcaaattgtatgctttctgaatatagactttctgggaaaaggtttactgctc
gtaaggaaacattttatgtattaa.aataaa.ctgt
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