рис. 3 pat


                   Нуклеотидная (кДНК) и аминокислотная
                   последовательности гена ФАГ человека

                  CTTCATCGTCGTCCAACTGACCTTGAGTGTTAGTTTCGCGGT
AAGTTTGGGTATAAGTGCCACCACCAGTGCCGGCAGTGTAGTCAGTAGTTTGTTGCTGGA
AGTCGTTACCGCCAAACTGCGTGTTACCGCCTAGATTAGACTGTGGCTGCTGGCGTTGAG
GGAAACCTGCCTGTACGTGAGGCCCTAAAAAGCCAGAGACCTCACTCCCGGGGAGCCAGC

ATG TCC ACT GCG GTC CTG GAA AAC CCA GGC TTG GGC AGG AAA CTC
Met ser thr ala val leu glu asn pro gly leu gly arg lys leu	15

TCT GAC TTT GGA CAG GAA ACA AGC TAT ATT GAA GAC AAC TGC AAT
ser asp phe gly gln glu thr ser tyr ile glu asp asn cys asn	30

CAA AAT GGT GCC ATA TCA CTG ATC TTC TCA CTC AAA GAA GAA GTT
gln asn gly ala ile ser leu ile phe ser leu lys glu glu val	45

GGT GCA TTG GCC AAA GTA TTG CGC TTA TTT GAG GAG AAT GAT GTA
gly ala leu ala lys val leu arg leu phe glu glu asn asp val	60

AAC CTG ACC CAC ATT GAA TCT AGA CCT TCT CGT TTA AAG AAA GAT
asn leu thr his ile glu ser arg pro ser arg leu lys lys asp	75

GAG TAT GAA TTT TTC ACC CAT TTG GAT AAA CGT AGC CTG CCT GCT
glu tyr glu phe phe thr his leu asp lys arg ser leu pro ala	90

CTG ACA AAC ATC ATC ATG ATC TTG AGG CAT GAC ATT GGT GCC ACT
leu thr asn ile ile lys ile leu arg his asp ile gly ala thr	105

GTC CAT GAG CTT TCA CGA GAT AAG AAG AAA GAC ACA GTG CCC TGG
val his glu leu ser arg asp lys lys lys asp thr val pro trp	120

TTC CCA AGA ACC ATT CAA GAG CTG GAC AGA TTT GCC AAT CAG ATT
phe pro arg thr ile gln glu leu asp arg phe ala asn gln ile	135

CTC AGC TAT GGA GCG GAA CTG GAT GCT GAC CAC CCT GGT TTT AAA
leu ser tyr gly ala glu leu asp ala asp his pro gly phe lys	150

GAT CCT GTG TAC CGT GCA AGA CGG AAG CAG TTT GCT GAC ATT GCC
asp pro val tyr arg ala arg arg lys gln phe ala asp ile ala	165

TAC AAC TAC CGC CAT GGG CAG CCC ATC CCT CGA GTG GAA TAC ATG
tyr asn tyr arg his gly gln pro ile pro arg val glu tyr met	180

GAG GAA GAA AAG AAA ACA TGG GGC ACA GTG TTC AAG ACT CTG AAG
glu glu glu lys lys thr trp gly thr val phe lys thr leu lys	195

TCC TTG TAT AAA ACC CAT GCT TGC TAT GAG TAC AAT CAC ATT TTT
ser leu tyr lys thr his ala cys tyr glu tyr asn his ile phe	210

CCA CTT CTT GAA AAG TAC TGT GGC TTC CAT GAA GAT AAC ATT CCC
pro leu leu glu lys tyr cys gly phe his glu asp asn ile pro	225

CAG CTG GAA GAC GTT TCT CAA TTC CTG CAG ACT TGC ACT GGT TTC
gln leu glu asp val ser gln phe leu gln thr cys thr gly phe	240

CGC CTC CGA CCT GTG GCT GGC CTG CTT TCC TCT CGG GAT TTC TTG
arg leu arg pro val ala gly leu leu ser ser arg asp phe leu	255

GGT GGC CTG GCC TTC CGA GTC TTC CAC TGC ACA CAG TAC ATC AGA
gly gly leu ala phe arg val phe his cys thr gln tyr ile arg	270

CAT GGA TCC AAG CCC ATG TAT ACC CCC GAA CCT GAC ATC TGC CAT
his gly ser lys pro met tyr thr pro glu pro asp ile cys his	285

GAG CTG TTG GGA CAT GTG CCC TTG TTT TCA GAT CGC AGC TTT GCC
glu leu leu gly his val pro leu phe ser asp arg ser phe ala	300

CAG TTT TCC CAG GAA ATT GGC CTT GCC TCT CTG GGT GCA CCT GAT
gln phe ser gln glu ile gly leu ala ser leu gly ala pro asp	315

GAA TAC ATT GAA AAG CTC GCC ACA ATT TAC TGG TTT ACT GTG GAG
glu tyr ile glu lys leu ala thr ile tyr trp phe thr val glu	330

TTT GGG CTC TGC AAA CAA GGA GAC TCC ATA AAG GCA TAT GGT GCT
phe gly leu cys lys gln gly asp ser ile lys ala tyr gly ala	345

GGG CTC CTG TCA TCC TTT GGT GAA TTA CAG TAC TGC TTA TCA GAG
gly leu leu ser ser phe gly glu leu gln tyr cys leu ser glu	360

AAG CCA AAG CTT CTC CCC CTG GAG CTG CAG AAG ACA GCC ATC CAA
lys pro lys leu leu pro leu glu leu glu lys thr ala ile gln	375

AAT TAC ACT GTC ACG GAG TTC CAG CCC CTG TAT TAC GTG GCA GAG
asn tyr thr val thr glu phe gln pro leu tyr tyr val ala glu	390

AGT TTT AAT GAT GCC AAG GAG AAA ATA AGG AAC TTT GCT GCC ACA
ser phe asn asp ala lys glu lys val arg asn phe ala ala thr	405

ATA CCT CGG CCC TTC TCA GTT CGC TAC GAC CCA TAC ACC CAA AGG
ile pro arg pro phe ser val arg tyr asp pro tyr thr gln arg	420

ATT GAG GTC TTG GAC AAT ACC CAG CAG CTT AAG ATT TTG GCT GAT
ile glu val leu asp asn thr gln gln leu lys ile leu ala asp	435
	
TCC ATT AAC AGT GAA ATT GGA ATC CTT TGC AGT GCC CTC CAG AAA
ser ile asn ser glu ile gly ile leu cys ser ala leu gln lys	450

ATA AAG TAA AGCCATGGACAGAATGTGGTCTGTCAGCTGTGAATCTGTTGATGGAGA
ile lys ter

TCCAACTATTTCTTTCATCAGAAAAAGTCCGAAAAGCAAACCTTAATTTGAAATAACAGC
CTTAAATCCTTTACAAGATGGAGAAACAACAAATAAGTCAAAATAATCTGAAATGACAGG
ATATGAGTACATACTCAAGAGCATAATGGTAAATCTTTTGGGGTCATCTTTGATTTAGAG
ATGATAATCCCATACTCTCAATTGAGTTAAATCAGTAATCTGTCGCATTTCATCAAGATT
AATTAAAATTTGGGACCTGCTTCATTCAAGCTTCATATATGCTTTGCAGACAACTCATAA
AGGAGCATATAAGGCTAAATGTAAAACACAAGACTGTCATTAGAATTGAATTATTGGGCT
TAATATAAATCGTAACCTATGAAGTTTATTTTCTATTTTAGTTAACTATGATTCCAATTA
CTACTTTGTTATTGTACCTAAGTAAATTTTCTTTAGGTCAGAAGCCCATTAAAATAGTTA
CAAGCATTGAACTTCTTTAGTATTATATTAATATAAAAACATTTTTGTATGTTTTATTGT
AATCATAAATACTGCTGTATAAGGTAATAAAACTCTGCACCTAATCCCCATAACTTCCAG
TATCATTTTCCAATTAATTATCAAGTCTGTTTTGGGAAACACTTTGAGGACATTTATGAT
GCAGCAGATGTTGACTAAAGGCTTGGTTGGTAGATATTCAGGAAATGTTCACTGAATAAA
TAAGTAAATACATTATTGAAAAGCAAATCTGTATAAATGTGAAATTTTTATTTGTATTAG
TAATAAAACATTAGTAGTTTAAAAAAAAAAAAAAAAAAA


Смотрите также:

  • Ген фенилаланингидроксилазы (ФАГ)