рис. 5 pat


Нуклеотидная (мРНК) и аминокислотная
              последовательности дигидроптеридин
                     редуктазы (DHPR)

                                      gtggcctaccatggtttcaac
gggtaacggggaataagggttcgattcggagctgcgggagccgggctggcaggagcagg

atg gcg gcg gcg gcg gct gca ggc gag gcg cgc cgg gtg ctg gtg
met ala ala ala ala ala ala gly glu ala arg arg val leu val  15

tac ggc ggc agg ggc gct ctg ggt tct cga tgc gtg cag gct ttt
tyr gly gly arg gly ala leu sly ser arg cys val gln ala phe  30

cgg gcc cgc aac tgg tgg gtt gcc agc gtt gat gtg gtg gag aat
arg ala arg asn trp trp val ala ser val asp val val glu asn  45

gaa gag gcc agc gct acg atc att gtt aaa atg aca gac tcg ttc
glu glu ala ser ala thr ile ile val lys met thr asp ser phe  60

act gag cag gct gac cag gtg act gct gag gtt gga aag ctc ttg
thr glu gln ala asp gln val thr ala glu val gly lys leu leu  75

ggt gaa gag aag gtg gat gca att ctt tgc gtt gct gga gga tgg
gly glu glu lys val asp ala ile leu cys val ala gly gly trp  90

gcc ggg ggc aat gcc aaa tcc aag tct ctc ttt aag aac tgt gac
ala gly gly asn ala lys ser lys ser leu phe lys asn cys asp 105

ctg atg tgg aag cag agc ata tgg aca tcg acc atc tcc agc cat
leu met trp lys gln ser ile trp thr ser thr ile ser ser his 120

ctg gct acc aag cat ctc aag gaa gga ggc ctc ctg acc ttg gct
leu ala thr lys his leu lys glu gly gly leu leu thr leu ala 135

ggc gca aag gct gcc ctg gat ggg act cct ggt atg atc ggg tac
gly ala lys ala ala leu asp gly thr pro gly met ile gly tyr 150

ggc atg gcc aag ggt gct gtt cac cag ctc tgc cag agc ctg gct
gly met ala lys gly ala val his gln leu cys gln ser leu ala 165

ggg aag aac agc ggc atg ccg ccc ggg gca gcc gcc atc gct gtg
gly lys asn ser gly met pro pro gly ala ala ala ile ala val 180

ctc ccg gtt acc ctg gat acc ccg atg aac agg aaa tca atg cct
leu pro val thr leu asp thr pro met asn arg lys ser met pro 195

gag gct gac ttc agc tcc tgg aca ccc tta gaa ttc cta gtt gaa
glu ala asp phe ser ser trp thr pro leu glu phe leu val glu 210

act ttc cat gac tgg atc aca ggg aaa aac cga ccg agc tca gga
thr phe his asp trp ile thr gly lys asn arg pro ser ser gly 225

agc cta atc cag gtg gta acc aca gaa gga agg acg gaa ctc acc
ser leu ile gln val val thr thr glu gly arg thr glu leu thr 240

cca gca tat ttt tag gcctcatctcagtgcctatgaggggcctgccagaaaagt
pro ala tyr phe ter

cactaacctgtctcagtgtggccttgtccagccttgtgttttctgtaacccctgtttgt
ggtacgagataatgagtcctatttttctctcacataatatgcatttgctctcctaggga
caagtgtaatacatttatgtgaagtaagacaatgcgagactggtggccgtcaaatagca
tccgtcaatctgtgttaactgcataggaggctctcgatagcacctgctatagcggtgtc
atgttggatcgctttgtgactgttcatctgtccttgacagtggctgtcatcttgactac
tttgttgatttgttggtattggggacattttaaaggctgagttatttttgaatgtcatg
tttatgtcatagacgtagaaaacgcatccttgaattaaactgccttaactccttttgtg
gtataagcaaactacatggactctgtccctggtatccttttcctgtgtggttgcccctg
tgcctgtggtctggcctaggttaagtgtgcaagataactactcgtgagttattcagaat
gttgttcctaataaatgcacttgttgtctgtcttctttaatcaaatcacatcttatata
cagcagtcagagatgagtatactagaatcatggattgctggaggtcttttaatctgatg
ttctcagaagggggtggatttaaatcctgaaataaatatttcaacac



















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