Рис. HPRT seq
Нуклеотидная и аминокислотная последовательности гена гипоксантин фосфорибозил трасферазы hypoxanthine phosphoribosyltransferase 1 (HPRT 1) человека ATG GCG ACC CGC AGC CCT GGC GTC GTG ATT AGT GAT GAT GAA CCA met ala thr arg ser pro gly val val ile ser asp asp glu pro 15 GGT TAT GAC CTT GAT TTA TTT TGC ATA CCT AAT CAT TAT GCT GAG gly tyr asp leu asp leu phe cys ile pro asn his tyr ala glu 30 GAT TTG GAA AGG GTG TTT ATT CCT CAT GGA CTA ATT ATG GAC AGG asp leu glu arg val phe ile pro his gly leu ile met asp arg 45 ACT GAA CGT CTT GCT CGA GAT GTG ATG AAG GAG ATG GGA GGC CAT thr glu arg leu ala arg asp val met lys glu met gly gly his 60 CAC ATT GTA GCC CTC TGT GTG CTC AAG GGG GGC TAT AAA TTC TTT his ile val ala leu cys val leu lys gly gly tyr lys phe phe 75 GCT GAC CTG CTG GAT TAC ATC AAA GCA CTG AAT AGA AAT AGT GAT ala asp leu leu asp tyr ile lys ala leu asn arg asn ser asp 90 AGA TCC ATT CCT ATG ACT GTA GAT TTT ATC AGA CTG AAG AGC TAT arg ser ile pro met the val asp phe ile arg leu lys ser tyr 105 TGT AAT GAC CAG TCA ACA GGG GAC ATA AAA GTA ATT GGT GGA GAT cys asn asp gln ser thr gly asp ile lys val ile gly gly asp 120 GAT CTC TCA ACT TTA ACT GGA AAG AAT GTC TTG ATT GTG GAA GAT asp leu ser thr leu thr gly lys asn val leu ile val glu asp 135 ATA ATT GAC ACT GGC AAA ACA ATG CAG ACT TTG CTT TCC TTG GTC ile ile asp thr gly lys thr met gln thr leu leu ser leu val 150 AGG CAG TAT AAT CCA AAG ATG GTC AAG GTC GCA AGC TTG CTG GTG arg gln tyr asn pro lys met val lys val ala ser leu leu val 165 AAA AGG ACC CCA CGA AGT GTT GGA TAT AAG CCA GAC TTT GTT GGA lys arg thr pro arg ser val gly tyr lys pro asp phe val gly 180 TTT GAA ATT CCA GAC AAG TTT GTT GTA GGA TAT GCC CTT GAC TAT phe glu ile pro asp lys phe val val gly tyr ala leu asp tyr 195 AAT GAA TAC TTC AGG GAT TTG AAT CAT GTT TGT GTC ATT AGT GAA asn glu tyr phe arg asp leu asn his val cys val ile ser glu 210 ACT GGA AAA GCA AAA TAC AAA GCC TAA thr gly lys ala lys tyr lys ala ter
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