Рис. SLC3A1 seq
Нуклеотидная и аминокислотная последовательности
гена транспортного белка аминокислоты цистина
(SLC3A) человека
ATG GCT GAA GAT AAA AGC AAG AGA GAC TCC ATC GAG ATG AGT ATG
met ala glu asp lys ser lys arg asp ser ile glu met ser met 15
AAG GGA TGC CAG ACA AAC AAC GGG TTT GTC CAT AAT GAA GAC ATT
lys gly cys gln thr asn asn gly phe val his asn glu asp ile 30
CTG GAG CAG ACC CCG GAT CCA GGC AGC TCA ACA GAC AAC CTG AAG
leu glu gln thr pro asp pro gly ser ser thr asp asn leu lys 45
CAC AGC ACC AGG GGC ATC CTT GGC TCC CAG GAG CCC GAC TTC AAG
his ser thr arg gly ile leu gly ser gln glu pro asp phe lys 60
GGC GTC CAG CCC TAT GCG GGG ATG CCC AAG GAG GTG CTG TTC CAG
gly val gln pro tyr ala gly met pro lys glu val leu phe gln 75
TTC TCT GGC CAG GCC CGC TAC CGC ATA CCT CGG GAG ATC CTC TTC
phe ser gly gln ala arg tyr arg ile pro arg glu ile leu phe 90
TGG CTC ACA GTG GCT TCT GTG CTG GTG CTC ATC GCG GCC ACC ATA
trp leu thr val ala ser val leu val leu ile ala ala thr ile 105
GCC ATC ATT GCC CTC TCT CCA AAG TGC CTA GAC TGG TGG CAG GAG
ala ile ile ala leu ser pro lys cys leu asp trp trp gln glu 120
GGG CCC ATG TAC CAG ATC TAC CCA AGG TCT TTC AAG GAC AGT AAC
gly pro met tyr gln ile tyr pro arg ser phe lys asp ser asn 135
AAG GAT GGG AAC GGA GAT CTG AAA GGT ATT CAA GAT AAA CTG GAC
lys asp gly asn gly asp leu lys gly ile gln asp lys leu asp 150
TAC ATC ACA GCT TTA AAT ATA AAA ACT GTT TGG ATT ACT TCA TTT
tyr ile thr ala leu asn ile lys thr val trp ile thr ser phe 165
TAT AAA TCG TCC CTT AAA GAT TTC AGA TAT GGT GTT GAA GAT TTC
tyr lys ser ser leu lys asp phe arg tyr gly val glu asp phe 180
CGG GAA GTT GAT CCC ATT TTT GGA ACG ATG GAA GAT TTT GAG AAT
arg glu val asp pro ile phe gly thr met glu asp phe glu asn 195
CTG GTT GCA GCC ATA CAT GAT AAA GGT TTA AAA TTA ATC ATC GAT
leu val ala ala ile his asp lys gly leu lys leu ile ile asp 210
TTC ATA CCA AAC CAC ACG AGT GAT AAA CAT ATT TGG TTT CAA TTG
phe ile pro asn his thr ser asp lys his ile trp phe gln leu 225
AGT CGG ACA CGG ACA GGA AAA TAT ACT GAT TAT TAT ATC TGG CAT
ser arg thr arg thr gly lys tyr thr asp tyr tyr ile trp his 240
GAC TGT ACC CAT GAA AAT GGC AAA ACC ATT CCA CCC AAC AAC TGG
asp cys thr his glu asn gly lys thr ile pro pro asn asn trp 255
TTA AGT GTG TAT GGA AAC TCC AGT TGG CAC TTT GAC GAA GTG CGA
leu ser val tyr gly asn ser ser trp his phe asp glu val arg 270
AAC CAA TGT TAT TTT CAT CAG TTT ATG AAA GAG CAA CCT GAT TTA
asn gln cys tyr phe his gln phe met lys glu gln pro asp leu 285
AAT TTC CGC AAT CCT GAT GTT CAA GAA GAA ATA AAA GAA ATT TTA
asn phe arg asn pro asp val gln glu glu ile lys glu ile leu 300
CGG TTC TGG CTC ACA AAG GGT GTT GAT GGT TTT AGT TTG GAT GCT
arg phe trp leu thr lys gly val asp gly phe ser leu asp ala 315
GTT AAA TTC CTC CTA GAA GCA AAG CAC CTG AGA GAT GAG ATC CAA
val lys phe leu leu glu ala lys his leu arg asp glu ile gln 330
GTA AAT AAG ACC CAA ATC CCG GAC ACG GTC ACA CAA TAC TCG GAG
val asn lys thr gln ile pro asp thr val thr gln tyr ser glu 345
CTG TAC CAT GAC TTC ACC ACC ACG CAG GTG GGA ATG CAC GAC ATT
leu tyr his asp phe thr thr thr gln val gly met his asp ile 360
GTC CGC AGC TTC CGG CAG ACC ATG GAC CAA TAC AGC ACG GAG CCC
val arg ser phe arg gln thr met asp gln tyr ser thr glu pro 375
GGC AGA TAC AGG TTC ATG GGG ACT GAA GCC TAT GCA GAG AGT ATT
gly arg tyr arg phe met gly thr glu ala tyr ala glu ser ile 390
GAC AGG ACC GTG ATG TAC TAT GGA TTG CCA TTT ATC CAA GAA GCT
asp arg thr val met tyr tyr gly leu pro phe ile gln glu ala 405
GAT TTT CCC TTC AAC AAT TAC CTC AGC ATG CTA GAC ACT GTT TCT
asp phe pro phe asn asn tyr leu ser met leu asp thr val ser 420
GGG AAC AGC GTG TAT GAG GTT ATC ACA TCC TGG ATG GAA AAC ATG
gly asn ser val tyr glu val ile thr ser trp met glu asn met 435
CCA GAA GGA AAA TGG CCT AAC TGG ATG ATT GGT GGA CCA GAC AGT
pro glu gly lys trp pro asn trp met ile gly gly pro asp ser 450
TCA CGG CTG ACT TCG CGT TTG GGG AAT CAG TAT GTC AAC GTG ATG
ser arg leu thr ser arg leu gly asn gln tyr val asn val met 465
AAC ATG CTT CTT TTC ACA CTC CCT GGA ACT CCT ATA ACT TAC TAT
asn met leu leu phe thr leu pro gly thr pro ile thr tyr tyr 480
GGA GAA GAA ATT GGA ATG GGA AAT ATT GTA GCC GCA AAT CTC AAT
gly glu glu ile gly met gly asn ile val ala ala asn leu asn 495
GAA AGC TAT GAT ATT AAT ACC CTT CGC TCA AAG TCA CCA ATG CAG
glu ser tyr asp ile asn thr leu arg ser lys ser pro met asn 510
TGG GAC AAT AGT TCA AAT GCT GGT TTT TCT GAA GCT AGT AAC ACC
trp asp asn ser ser asn ala gly phe ser glu ala ser asn thr 525
TGG TTA CCT ACC AAT TCA GAT TAC CAC ACT GTG AAT GTT GAT GTC
trp leu pro thr asn ser asp tyr his thr val asn val asp val 540
CAA AAG ACT CAG CCC AGA TCG GCT TTG AAG TTA TAT CAA GAT TTA
gln lys thr gln pro arg ser ala leu lys leu tyr gln asp leu 555
AGT CTA CTT CAT GCC AAT GAG CTA CTC CTC AAC AGG GGC TGG TTT
ser leu leu his ala asn glu leu leu leu asn arg gly trp phe 570
TGC CAT TTG AGG AAT GAC AGC CAC TAT GTT GTG TAC ACA AGA GAG
cys his leu arg asn asp ser his tyr val val tyr thr arg glu 585
CTG GAT GGC ATC GAC AGA ATC TTT ATC GTG GTT CTG AAT TTT GGA
leu asp gly ile asp arg ile phe ile val val leu asn phe gly 600
GAA TCA ACA CTG TTA AAT CTA CAT AAT ATG ATT TCG GGC CTT CCC
glu ser thr leu leu asn leu his asn met ile ser gly leu pro 615
GCT AAA ATA AGA ATA AGG TTA AGT ACC AAT TCT GCC GAC AAA GGC
ala lys ile arg ile arg leu ser thr asn ser ala asp lys gly 630
AGT AAA GTT GAT ACA AGT GGC ATT TTT CTG GAC AAG GGA GAG GGA
ser lys val asp thr ser gly ile phe leu asp lys gly glu gly 645
CTC ATC TTT GAA CAC AAC ACG AAG AAT CTC CTT CAT CGC CAA ACA
leu ile phe glu his asn thr lys asn leu leu his arg gln thr 660
GCT TTC AGA GAT AGA TGC TTT GTT TCC AAT CGA GCA TGC TAT TCC
ala phe arg asp arg cys phe val ser asn arg ala cys tyr ser 675
AGT GTA CTG AAC ATA CTG TAT ACC TCG TGT TAG
ser val leu asn ile leu tyr thr ser cys ter
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