Entry - *109710 - BETA-2-MICROGLOBULIN REGULATOR; B2MR - OMIM

 
 
* 109710

BETA-2-MICROGLOBULIN REGULATOR; B2MR


HGNC Approved Gene Symbol: B2MR

Cytogenetic location: 15q13-q15     Genomic coordinates (GRCh38): 15:27,800,001-44,500,000


TEXT

▼ Mapping

Two groups assigned the beta-2-microglobulin (B2M) regulator locus to chromosome 15 by dosage effect (Manolov et al., 1979; Zhang and Zech, 1981). The regional assignment was 15q13-q15. Cell lines lacking this locus through chromosomal deletion produced B2M but did not insert it into the cell membrane.

▼ REFERENCES

  1. Manolov, G., Manolova, Y., Kieler, J. Cytogenetical investigation of assignment of locus for beta-2-microglobulin in K562 leukemia and Namalwa and Daudi Burkitt lymphoma cells. (Abstract) Cytogenet. Cell Genet. 25: 182 only, 1979.

  2. Zhang, S., Zech, L. Marker chromosomes in cell lines from Burkitt's lymphoma; analysis of break points by high resolution techniques. (Abstract) Sixth International Congress of Human Genetics, Jerusalem 1981. P. 208.


Creation Date:
Victor A. McKusick : 6/4/1986
Edit History:
mgross : 10/12/2020
carol : 10/13/2016
alopez : 08/22/2012
supermim : 3/16/1992
supermim : 3/20/1990
ddp : 10/26/1989
marie : 3/25/1988
marie : 10/23/1986
reenie : 6/4/1986

* 109710

BETA-2-MICROGLOBULIN REGULATOR; B2MR


HGNC Approved Gene Symbol: B2MR

Cytogenetic location: 15q13-q15     Genomic coordinates (GRCh38): 15:27,800,001-44,500,000


TEXT

Mapping

Two groups assigned the beta-2-microglobulin (B2M) regulator locus to chromosome 15 by dosage effect (Manolov et al., 1979; Zhang and Zech, 1981). The regional assignment was 15q13-q15. Cell lines lacking this locus through chromosomal deletion produced B2M but did not insert it into the cell membrane.

REFERENCES

  1. Manolov, G., Manolova, Y., Kieler, J. Cytogenetical investigation of assignment of locus for beta-2-microglobulin in K562 leukemia and Namalwa and Daudi Burkitt lymphoma cells. (Abstract) Cytogenet. Cell Genet. 25: 182 only, 1979.

  2. Zhang, S., Zech, L. Marker chromosomes in cell lines from Burkitt's lymphoma; analysis of break points by high resolution techniques. (Abstract) Sixth International Congress of Human Genetics, Jerusalem 1981. P. 208.


Creation Date:
Victor A. McKusick : 6/4/1986

Edit History:
mgross : 10/12/2020
carol : 10/13/2016
alopez : 08/22/2012
supermim : 3/16/1992
supermim : 3/20/1990
ddp : 10/26/1989
marie : 3/25/1988
marie : 10/23/1986
reenie : 6/4/1986



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 2, 2024