Cytogenetic location: 4q28-q31 Genomic coordinates (GRCh38): 4:122,800,001-154,600,000
| Location | Phenotype |
Phenotype MIM number |
Inheritance |
Phenotype mapping key |
|---|---|---|---|---|
| 4q28-q31 | [Blood group, Stoltzfus system] | 111800 | 2 |
An antibody that tests for an antigen in a seemingly 'new' blood group system was found in the Lancaster County Amish (Bias et al., 1969). It has been designated Stoltzfus, symbolized Sf. For males, Bias and Meyers (1979) found a maximal lod score of 3.99 at theta 0.18 for Stoltzfus and MNS. Acid phosphatase and Kidd both gave lods of 0.32 with Stoltzfus at a male theta of 0.20. Bias and Meyers (1982) presented additional data bringing the maximum lods to 5.01 for theta 0.25 in males and 3.05 for theta 0.27 in females.
Data on gene frequencies of allelic variants were tabulated by Roychoudhury and Nei (1988).
Bias, W. B., Light-Orr, J. K., Krevans, J. R., Humphrey, R. L., Hamill, P. V. V., Cohen, B. H., McKusick, V. A. The Stoltzfus blood group, a new polymorphism in man. Am. J. Hum. Genet. 21: 552-558, 1969. [PubMed: 5365757]
Bias, W. B., Meyers, D. A. Segregation and linkage analysis of the Stoltzfus blood group (SF). (Abstract) Cytogenet. Cell Genet. 25: 137 only, 1979.
Bias, W. B., Meyers, D. A. Further data on the linkage between MNS and Stoltzfus blood group systems. (Abstract) Cytogenet. Cell Genet. 32: 254 only, 1982.
Roychoudhury, A. K., Nei, M. Human Polymorphic Genes: World Distribution. New York: Oxford Univ. Press (pub.) 1988.