Entry - *118495 - CHOLINERGIC RECEPTOR, MUSCARINIC, 4; CHRM4 - OMIM

 
 
* 118495

CHOLINERGIC RECEPTOR, MUSCARINIC, 4; CHRM4


Alternative titles; symbols

ACETYLCHOLINE RECEPTOR, MUSCARINIC, 4


HGNC Approved Gene Symbol: CHRM4

Cytogenetic location: 11p11.2     Genomic coordinates (GRCh38): 11:46,383,789-46,391,776 (from NCBI)


TEXT

▼ Description

For a general description of muscarinic cholinergic receptors, see 118510.

▼ Mapping

Detera-Wadleigh et al. (1989) described an SstI polymorphism for the CHRM4 gene. They stated that the gene maps to 11p. By the study of somatic cell hybrids and by both isotopic and nonisotopic in situ hybridization, Bonner et al. (1991) assigned the CHRM4 gene to 11p12-p11.2. Grewal et al. (1992) mapped the CHRM4 gene to the same region by linkage with DNA markers.


▼ REFERENCES

  1. Bonner, T. I., Modi, W. S., Seuanez, H. N., O'Brien, S. J. Chromosomal mapping of five human genes encoding muscarinic acetylcholine receptors. (Abstract) Cytogenet. Cell Genet. 58: 1850-1851, 1991.

  2. Detera-Wadleigh, S. D., Wiesch, D., Bonner, T. I. An SstI polymorphism for the human muscarinic acetylcholine receptor gene, m4 (CHRM4). Nucleic Acids Res. 17: 6431 only, 1989. [PubMed: 2570410, related citations] [Full Text]

  3. Grewal, R. P., Martinez, M., Hoehe, M., Bonner, T. I., Gershon, E. S., Detera-Wadleigh, S. Genetic linkage mapping of the m4 human muscarinic receptor (CHRM4). Genomics 13: 239-240, 1992. [PubMed: 1577490, related citations] [Full Text]


Creation Date:
Victor A. McKusick : 9/9/1990
Edit History:
carol : 06/17/2021
carol : 02/27/2004
carol : 5/22/1992
supermim : 3/16/1992
carol : 3/4/1992
carol : 2/21/1992
carol : 8/8/1991
supermim : 9/28/1990

* 118495

CHOLINERGIC RECEPTOR, MUSCARINIC, 4; CHRM4


Alternative titles; symbols

ACETYLCHOLINE RECEPTOR, MUSCARINIC, 4


HGNC Approved Gene Symbol: CHRM4

Cytogenetic location: 11p11.2     Genomic coordinates (GRCh38): 11:46,383,789-46,391,776 (from NCBI)


TEXT

Description

For a general description of muscarinic cholinergic receptors, see 118510.

Mapping

Detera-Wadleigh et al. (1989) described an SstI polymorphism for the CHRM4 gene. They stated that the gene maps to 11p. By the study of somatic cell hybrids and by both isotopic and nonisotopic in situ hybridization, Bonner et al. (1991) assigned the CHRM4 gene to 11p12-p11.2. Grewal et al. (1992) mapped the CHRM4 gene to the same region by linkage with DNA markers.


REFERENCES

  1. Bonner, T. I., Modi, W. S., Seuanez, H. N., O'Brien, S. J. Chromosomal mapping of five human genes encoding muscarinic acetylcholine receptors. (Abstract) Cytogenet. Cell Genet. 58: 1850-1851, 1991.

  2. Detera-Wadleigh, S. D., Wiesch, D., Bonner, T. I. An SstI polymorphism for the human muscarinic acetylcholine receptor gene, m4 (CHRM4). Nucleic Acids Res. 17: 6431 only, 1989. [PubMed: 2570410] [Full Text: https://doi.org/10.1093/nar/17.15.6431]

  3. Grewal, R. P., Martinez, M., Hoehe, M., Bonner, T. I., Gershon, E. S., Detera-Wadleigh, S. Genetic linkage mapping of the m4 human muscarinic receptor (CHRM4). Genomics 13: 239-240, 1992. [PubMed: 1577490] [Full Text: https://doi.org/10.1016/0888-7543(92)90236-l]


Creation Date:
Victor A. McKusick : 9/9/1990

Edit History:
carol : 06/17/2021
carol : 02/27/2004
carol : 5/22/1992
supermim : 3/16/1992
carol : 3/4/1992
carol : 2/21/1992
carol : 8/8/1991
supermim : 9/28/1990



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 7, 2024