Entry - *142580 - PROLINE-RICH COILED-COIL PROTEIN 2A; PRRC2A - OMIM

 
 
* 142580

PROLINE-RICH COILED-COIL PROTEIN 2A; PRRC2A


Alternative titles; symbols

HLA-B-ASSOCIATED TRANSCRIPT 2; BAT2
D6S51E


HGNC Approved Gene Symbol: PRRC2A

Cytogenetic location: 6p21.33     Genomic coordinates (GRCh38): 6:31,620,715-31,637,771 (from NCBI)


TEXT

▼ Cloning and Expression

Banerji et al. (1990) determined the complete cDNA sequences of BAT2 and BAT3 (142590). BAT2 and BAT3 encode deduced proline-rich proteins of 2,142 and 1,132 residues with molecular masses of approximately 228 and 110 kD, respectively. The BAT2 sequence contains 4 RGD motifs, of which 3 are clustered within a 95-amino acid segment. BAT3 contains an N-terminal ubiquitin-like domain.


▼ Mapping

Banerji et al. (1990) stated that the BAT2 and BAT3 genes map within the class III region of the major histocompatibility complex on chromosome 6p21.3.


▼ REFERENCES

  1. Banerji, J., Sands, J., Strominger, J. L., Spies, T. A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain. Proc. Nat. Acad. Sci. 87: 2374-2378, 1990. [PubMed: 2156268, related citations] [Full Text]


Creation Date:
Victor A. McKusick : 2/2/1989
Edit History:
carol : 01/08/2014
alopez : 8/15/2011
carol : 7/18/2001
terry : 2/28/2000
carol : 2/22/1999
alopez : 9/5/1997
terry : 10/7/1994
supermim : 3/16/1992
supermim : 5/11/1990
supermim : 3/20/1990
carol : 3/9/1990
ddp : 10/27/1989

* 142580

PROLINE-RICH COILED-COIL PROTEIN 2A; PRRC2A


Alternative titles; symbols

HLA-B-ASSOCIATED TRANSCRIPT 2; BAT2
D6S51E


HGNC Approved Gene Symbol: PRRC2A

Cytogenetic location: 6p21.33     Genomic coordinates (GRCh38): 6:31,620,715-31,637,771 (from NCBI)


TEXT

Cloning and Expression

Banerji et al. (1990) determined the complete cDNA sequences of BAT2 and BAT3 (142590). BAT2 and BAT3 encode deduced proline-rich proteins of 2,142 and 1,132 residues with molecular masses of approximately 228 and 110 kD, respectively. The BAT2 sequence contains 4 RGD motifs, of which 3 are clustered within a 95-amino acid segment. BAT3 contains an N-terminal ubiquitin-like domain.


Mapping

Banerji et al. (1990) stated that the BAT2 and BAT3 genes map within the class III region of the major histocompatibility complex on chromosome 6p21.3.


REFERENCES

  1. Banerji, J., Sands, J., Strominger, J. L., Spies, T. A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain. Proc. Nat. Acad. Sci. 87: 2374-2378, 1990. [PubMed: 2156268] [Full Text: https://doi.org/10.1073/pnas.87.6.2374]


Creation Date:
Victor A. McKusick : 2/2/1989

Edit History:
carol : 01/08/2014
alopez : 8/15/2011
carol : 7/18/2001
terry : 2/28/2000
carol : 2/22/1999
alopez : 9/5/1997
terry : 10/7/1994
supermim : 3/16/1992
supermim : 5/11/1990
supermim : 3/20/1990
carol : 3/9/1990
ddp : 10/27/1989



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 4, 2024