Entry - *187280 - POLYMERASE III, RNA, SUBUNIT D; POLR3D - OMIM

 
 
* 187280

POLYMERASE III, RNA, SUBUNIT D; POLR3D


Alternative titles; symbols

TEMPERATURE SENSITIVITY COMPLEMENTATION, CELL CYCLE SPECIFIC, tsBN51; BN51T
TSBN51


HGNC Approved Gene Symbol: POLR3D

Cytogenetic location: 8p21.3     Genomic coordinates (GRCh38): 8:22,245,133-22,254,601 (from NCBI)


TEXT

▼ Cloning and Expression

Ittmann et al. (1987) cloned human TSBN51, which complements the mutation of tsBN51, a temperature-sensitive cell cycle mutant of BHK cells that is blocked in G1 at nonpermissive temperature. TSBN51 encodes a highly charged protein of 395 amino acids.


▼ Mapping

Greco et al. (1989) assigned the TSBN51 gene to chromosome 8q21 by study of rodent-human hybrid cells and by in situ hybridization using a tsBN51 probe.


▼ REFERENCES

  1. Greco, A., Ittmann, M., Barletta, C., Basilico, C., Croce, C. M., Cannizzaro, L. A., Huebner, K. Chromosomal localization of human genes required for G(1) progression in mammalian cells. Genomics 4: 240-245, 1989. [PubMed: 2714790, related citations] [Full Text]

  2. Ittmann, M., Greco, A., Basilico, C. Isolation of the human gene that complements a temperature-sensitive cell cycle mutation in BHK cells. Molec. Cell. Biol. 7: 3386-3393, 1987. [PubMed: 3683386, related citations] [Full Text]


Creation Date:
Victor A. McKusick : 4/4/1989
Edit History:
carol : 11/27/2013
mgross : 3/18/2004
carol : 11/8/2002
supermim : 3/16/1992
supermim : 3/20/1990
carol : 11/22/1989
ddp : 10/27/1989
root : 9/10/1989
root : 4/4/1989

* 187280

POLYMERASE III, RNA, SUBUNIT D; POLR3D


Alternative titles; symbols

TEMPERATURE SENSITIVITY COMPLEMENTATION, CELL CYCLE SPECIFIC, tsBN51; BN51T
TSBN51


HGNC Approved Gene Symbol: POLR3D

Cytogenetic location: 8p21.3     Genomic coordinates (GRCh38): 8:22,245,133-22,254,601 (from NCBI)


TEXT

Cloning and Expression

Ittmann et al. (1987) cloned human TSBN51, which complements the mutation of tsBN51, a temperature-sensitive cell cycle mutant of BHK cells that is blocked in G1 at nonpermissive temperature. TSBN51 encodes a highly charged protein of 395 amino acids.


Mapping

Greco et al. (1989) assigned the TSBN51 gene to chromosome 8q21 by study of rodent-human hybrid cells and by in situ hybridization using a tsBN51 probe.


REFERENCES

  1. Greco, A., Ittmann, M., Barletta, C., Basilico, C., Croce, C. M., Cannizzaro, L. A., Huebner, K. Chromosomal localization of human genes required for G(1) progression in mammalian cells. Genomics 4: 240-245, 1989. [PubMed: 2714790] [Full Text: https://doi.org/10.1016/0888-7543(89)90326-1]

  2. Ittmann, M., Greco, A., Basilico, C. Isolation of the human gene that complements a temperature-sensitive cell cycle mutation in BHK cells. Molec. Cell. Biol. 7: 3386-3393, 1987. [PubMed: 3683386] [Full Text: https://doi.org/10.1128/mcb.7.10.3386-3393.1987]


Creation Date:
Victor A. McKusick : 4/4/1989

Edit History:
carol : 11/27/2013
mgross : 3/18/2004
carol : 11/8/2002
supermim : 3/16/1992
supermim : 3/20/1990
carol : 11/22/1989
ddp : 10/27/1989
root : 9/10/1989
root : 4/4/1989



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: April 29, 2024