Entry - *189933 - tRNA THREONINE (ANTICODON TGT) 3-1; TRT-TGT3-1 - OMIM

 
 
* 189933

tRNA THREONINE (ANTICODON TGT) 3-1; TRT-TGT3-1


Alternative titles; symbols

tRNA-THR (ANTICODON TGT) 3-1
TRANSFER RNA THREONINE 2; TRNAT2
tRNA THREONINE 2; TRT2


HGNC Approved Gene Symbol: TRT-TGT3-1

Cytogenetic location: 14q11.2     Genomic coordinates (GRCh38): 14:20,613,790-20,613,862 (from NCBI)


TEXT

▼ Cloning and Expression

Chang et al. (1986) isolated and sequenced a cluster of 4 tRNA genes arranged as 2 tandem pairs: proline tRNA(AGG) (TRP1; 189930) and leucine tRNA(AAG) (TRL1; 189932), followed by a second proline tRNA(AGG) (TRP2; 189931) and threonine tRNA(UGU) (TRT2).


▼ Mapping

Chang et al. (1986) determined that the TRP2 gene is 316 bp from the TRT2 gene. Mitchell et al. (1991) mapped the gene cluster containing TRT2 to chromosome 14q11 near the TCRA gene (see 186880).


▼ REFERENCES

  1. Chang, Y. N., Pirtle, I. L., Pirtle, R. M. Nucleotide sequence and transcription of a human tRNA gene cluster with four genes. Gene 48: 165-174, 1986. [PubMed: 3557125, related citations] [Full Text]

  2. Mitchell, A., Bale, A. E., Wang-ge, M., Yi, H. F., White, R., Pirtle, R. M., McBride, O. W. Localization of a DNA segment encompassing four tRNA genes to human chromosome 14q11 and its use as an anchor locus for linkage analysis. Genomics 11: 1063-1070, 1991. [PubMed: 1686015, related citations] [Full Text]


Contributors:
Paul J. Converse - updated : 3/5/2002
Creation Date:
Victor A. McKusick : 3/7/1990
Edit History:
mgross : 01/08/2021
mgross : 10/04/2013
alopez : 4/4/2012
carol : 8/31/2009
tkritzer : 11/20/2003
mgross : 3/5/2002
alopez : 7/26/1999
supermim : 3/16/1992
supermim : 3/22/1990
supermim : 3/20/1990
carol : 3/7/1990

* 189933

tRNA THREONINE (ANTICODON TGT) 3-1; TRT-TGT3-1


Alternative titles; symbols

tRNA-THR (ANTICODON TGT) 3-1
TRANSFER RNA THREONINE 2; TRNAT2
tRNA THREONINE 2; TRT2


HGNC Approved Gene Symbol: TRT-TGT3-1

Cytogenetic location: 14q11.2     Genomic coordinates (GRCh38): 14:20,613,790-20,613,862 (from NCBI)


TEXT

Cloning and Expression

Chang et al. (1986) isolated and sequenced a cluster of 4 tRNA genes arranged as 2 tandem pairs: proline tRNA(AGG) (TRP1; 189930) and leucine tRNA(AAG) (TRL1; 189932), followed by a second proline tRNA(AGG) (TRP2; 189931) and threonine tRNA(UGU) (TRT2).


Mapping

Chang et al. (1986) determined that the TRP2 gene is 316 bp from the TRT2 gene. Mitchell et al. (1991) mapped the gene cluster containing TRT2 to chromosome 14q11 near the TCRA gene (see 186880).


REFERENCES

  1. Chang, Y. N., Pirtle, I. L., Pirtle, R. M. Nucleotide sequence and transcription of a human tRNA gene cluster with four genes. Gene 48: 165-174, 1986. [PubMed: 3557125] [Full Text: https://doi.org/10.1016/0378-1119(86)90362-8]

  2. Mitchell, A., Bale, A. E., Wang-ge, M., Yi, H. F., White, R., Pirtle, R. M., McBride, O. W. Localization of a DNA segment encompassing four tRNA genes to human chromosome 14q11 and its use as an anchor locus for linkage analysis. Genomics 11: 1063-1070, 1991. [PubMed: 1686015] [Full Text: https://doi.org/10.1016/0888-7543(91)90033-b]


Contributors:
Paul J. Converse - updated : 3/5/2002

Creation Date:
Victor A. McKusick : 3/7/1990

Edit History:
mgross : 01/08/2021
mgross : 10/04/2013
alopez : 4/4/2012
carol : 8/31/2009
tkritzer : 11/20/2003
mgross : 3/5/2002
alopez : 7/26/1999
supermim : 3/16/1992
supermim : 3/22/1990
supermim : 3/20/1990
carol : 3/7/1990



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 3, 2024