Entry - *194526 - ZINC FINGER PROTEIN 34; ZNF34 - OMIM

 
 
* 194526

ZINC FINGER PROTEIN 34; ZNF34


Alternative titles; symbols

KOX32


HGNC Approved Gene Symbol: ZNF34

Cytogenetic location: 8q24.3     Genomic coordinates (GRCh38): 8:144,772,224-144,787,317 (from NCBI)


TEXT

▼ Cloning and Expression

KOX32 is a 1.4-kb cDNA fragment of the ZNF34 zinc finger gene cloned into the EcoRI site of a plasmid vector. La Pillo et al. (1993) described a BanII RFLP in the ZNF34 gene.


▼ Mapping

Huebner et al. (1991) mapped the ZNF34 gene to chromosome 8q24, proximal to MYC (190080) by somatic cell hybrid analysis and in situ chromosomal hybridization. Since MYC is located in 8q24.12-q24.13 and both genes were found to be intact in 2 patients with Langer-Giedion syndrome (150230) and a deletion of 8q22.3-q24.11 and 8q23.3-q24.12, respectively, La Pillo et al. (1993) concluded that ZNF34 is located in 8q24.12-q24.13.


▼ REFERENCES

  1. Huebner, K., Druck, T., Croce, C. M., Thiesen, H. J. Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering. Am. J. Hum. Genet. 48: 726-740, 1991. [PubMed: 2014798, related citations]

  2. La Pillo, B., Ludecke, H.-J., Thiesen, H.-J., Horsthemke, B. A BanII RFLP in the ZNF34 zinc finger gene on chromosome 8. Hum. Molec. Genet. 2: 1331, 1993. [PubMed: 8104631, related citations] [Full Text]


Creation Date:
Victor A. McKusick : 9/20/1993
Edit History:
alopez : 07/06/2010
dkim : 6/26/1998
mark : 5/14/1996
carol : 10/26/1993
carol : 9/20/1993

* 194526

ZINC FINGER PROTEIN 34; ZNF34


Alternative titles; symbols

KOX32


HGNC Approved Gene Symbol: ZNF34

Cytogenetic location: 8q24.3     Genomic coordinates (GRCh38): 8:144,772,224-144,787,317 (from NCBI)


TEXT

Cloning and Expression

KOX32 is a 1.4-kb cDNA fragment of the ZNF34 zinc finger gene cloned into the EcoRI site of a plasmid vector. La Pillo et al. (1993) described a BanII RFLP in the ZNF34 gene.


Mapping

Huebner et al. (1991) mapped the ZNF34 gene to chromosome 8q24, proximal to MYC (190080) by somatic cell hybrid analysis and in situ chromosomal hybridization. Since MYC is located in 8q24.12-q24.13 and both genes were found to be intact in 2 patients with Langer-Giedion syndrome (150230) and a deletion of 8q22.3-q24.11 and 8q23.3-q24.12, respectively, La Pillo et al. (1993) concluded that ZNF34 is located in 8q24.12-q24.13.


REFERENCES

  1. Huebner, K., Druck, T., Croce, C. M., Thiesen, H. J. Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering. Am. J. Hum. Genet. 48: 726-740, 1991. [PubMed: 2014798]

  2. La Pillo, B., Ludecke, H.-J., Thiesen, H.-J., Horsthemke, B. A BanII RFLP in the ZNF34 zinc finger gene on chromosome 8. Hum. Molec. Genet. 2: 1331, 1993. [PubMed: 8104631] [Full Text: https://doi.org/10.1093/hmg/2.8.1331-a]


Creation Date:
Victor A. McKusick : 9/20/1993

Edit History:
alopez : 07/06/2010
dkim : 6/26/1998
mark : 5/14/1996
carol : 10/26/1993
carol : 9/20/1993



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 6, 2024