Entry - *194542 - ZINC FINGER PROTEIN 44; ZNF44 - OMIM

 
 
* 194542

ZINC FINGER PROTEIN 44; ZNF44


Alternative titles; symbols

KOX7


HGNC Approved Gene Symbol: ZNF44

Cytogenetic location: 19p13.2     Genomic coordinates (GRCh38): 19:12,224,686-12,294,883 (from NCBI)


TEXT

▼ Cloning and Expression

Bray et al. (1991) screened a placental genomic library at moderate stringency with a degenerate oligodeoxynucleotide probe designed to hybridize to the his/cys (H/C) link region between adjoining zinc fingers. Genomic clones were cross-hybridized with a set of 30 zinc finger-encoding cDNAs (KOX1-KOX30) isolated from a human T-cell cDNA library. KOX7 matched one of the genomic clones.


▼ Mapping

Bray et al. (1991) mapped the ZNF44 gene to chromosome 16p11 by chromosomal in situ suppression hybridization with fluorescent probe detection. However, Gross (2011) mapped the ZNF44 gene to chromosome 19p13.2 based on an alignment of the ZNF44 sequence (GenBank BC136502) with the genomic sequence (GRCh37).


▼ REFERENCES

  1. Bray, P., Lichter, P., Thiesen, H.-J., Ward, D. C., Dawid, I. B. Characterization and mapping of human genes encoding zinc finger proteins. Proc. Nat. Acad. Sci. 88: 9563-9567, 1991. [PubMed: 1946370, related citations] [Full Text]

  2. Gross, M. B. Personal Communication. Baltimore, Md. 2/7/2011.


Contributors:
Matthew B. Gross - updated : 02/07/2011
Creation Date:
Victor A. McKusick : 12/4/1991
Edit History:
mgross : 02/07/2011
alopez : 7/7/2010
dkim : 6/26/1998
mark : 5/14/1996
supermim : 3/16/1992
carol : 12/4/1991

* 194542

ZINC FINGER PROTEIN 44; ZNF44


Alternative titles; symbols

KOX7


HGNC Approved Gene Symbol: ZNF44

Cytogenetic location: 19p13.2     Genomic coordinates (GRCh38): 19:12,224,686-12,294,883 (from NCBI)


TEXT

Cloning and Expression

Bray et al. (1991) screened a placental genomic library at moderate stringency with a degenerate oligodeoxynucleotide probe designed to hybridize to the his/cys (H/C) link region between adjoining zinc fingers. Genomic clones were cross-hybridized with a set of 30 zinc finger-encoding cDNAs (KOX1-KOX30) isolated from a human T-cell cDNA library. KOX7 matched one of the genomic clones.


Mapping

Bray et al. (1991) mapped the ZNF44 gene to chromosome 16p11 by chromosomal in situ suppression hybridization with fluorescent probe detection. However, Gross (2011) mapped the ZNF44 gene to chromosome 19p13.2 based on an alignment of the ZNF44 sequence (GenBank BC136502) with the genomic sequence (GRCh37).


REFERENCES

  1. Bray, P., Lichter, P., Thiesen, H.-J., Ward, D. C., Dawid, I. B. Characterization and mapping of human genes encoding zinc finger proteins. Proc. Nat. Acad. Sci. 88: 9563-9567, 1991. [PubMed: 1946370] [Full Text: https://doi.org/10.1073/pnas.88.21.9563]

  2. Gross, M. B. Personal Communication. Baltimore, Md. 2/7/2011.


Contributors:
Matthew B. Gross - updated : 02/07/2011

Creation Date:
Victor A. McKusick : 12/4/1991

Edit History:
mgross : 02/07/2011
alopez : 7/7/2010
dkim : 6/26/1998
mark : 5/14/1996
supermim : 3/16/1992
carol : 12/4/1991



NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 5, 2024