Entry - *194632 - ZINC FINGER PROTEIN 125; ZNF125 - OMIM

 
 
* 194632

ZINC FINGER PROTEIN 125; ZNF125


Cytogenetic location: 11q23.1-q23.2     Genomic coordinates (GRCh38): 11:110,600,001-114,600,000


TEXT

▼ Cloning and Expression

Using a degenerate oligonucleotide corresponding to the histidine/cysteine link consensus sequence of the Drosophila Kruppel zinc finger gene, Saleh et al. (1992) isolated the ZNF125 gene from an arrayed chromosome 11q cosmid library. Northern blot analysis detected expression of ZNF125 as multiple transcripts of 8.1, 5.9, and 3.8 kb in all human tissues examined with the exception of pancreas.


▼ Mapping

Using fluorescence in situ suppression hybridization (FISSH), Saleh et al. (1992) mapped the ZNF125 gene to chromosome 11q23.1-q23.2, near the ZNF123 gene (194630).


▼ REFERENCES

  1. Saleh, M., Selleri, L., Little, P. F. R., Evans, G. A. Isolation and expression of linked zinc finger gene clusters on human chromosome 11q. Genomics 14: 970-978, 1992. [PubMed: 1339395, related citations] [Full Text]


Creation Date:
Victor A. McKusick : 2/24/1993
Edit History:
alopez : 07/12/2010
dkim : 6/26/1998
carol : 2/24/1993

* 194632

ZINC FINGER PROTEIN 125; ZNF125


Cytogenetic location: 11q23.1-q23.2     Genomic coordinates (GRCh38): 11:110,600,001-114,600,000


TEXT

Cloning and Expression

Using a degenerate oligonucleotide corresponding to the histidine/cysteine link consensus sequence of the Drosophila Kruppel zinc finger gene, Saleh et al. (1992) isolated the ZNF125 gene from an arrayed chromosome 11q cosmid library. Northern blot analysis detected expression of ZNF125 as multiple transcripts of 8.1, 5.9, and 3.8 kb in all human tissues examined with the exception of pancreas.


Mapping

Using fluorescence in situ suppression hybridization (FISSH), Saleh et al. (1992) mapped the ZNF125 gene to chromosome 11q23.1-q23.2, near the ZNF123 gene (194630).


REFERENCES

  1. Saleh, M., Selleri, L., Little, P. F. R., Evans, G. A. Isolation and expression of linked zinc finger gene clusters on human chromosome 11q. Genomics 14: 970-978, 1992. [PubMed: 1339395] [Full Text: https://doi.org/10.1016/s0888-7543(05)80119-3]


Creation Date:
Victor A. McKusick : 2/24/1993

Edit History:
alopez : 07/12/2010
dkim : 6/26/1998
carol : 2/24/1993



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: April 29, 2024