Alternative titles; symbols
HGNC Approved Gene Symbol: TMEM187
Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:153,972,754-153,983,194 (from NCBI)
Faranda et al. (1996) isolated the ITBA1 gene, which has an open reading frame encoding 261 amino acids and is ubiquitously expressed. See also ITBA2 (300060).
Faranda et al. (1996) identified a ITBA1 gene about 2 kb downstream from HCFC1 (300019), the host cell factor C1 gene located on Xq28. They identified the gene by using an approach that coupled genomic sequencing and EST database searching. Because the sequences came from CpG islands in the proximity of HCFC1 and GDX (312070), ITBA1 was known to be located in the interval between L1CAM (308840) and G6PD (305900).
Faranda (1996) stated that the designation of the ITBA gene was arbitrarily chosen from the acronym of the institute where she works, Istituto di Tecnologie Biomediche Avanzate, in Milan, Italy.
Faranda, S. Personal Communication. Milan, Italy 7/18/1996.
Faranda, S., Frattini, A., Zucchi, I., Patrosso, C., Milanes, L., Montagna, C., Vezzoni, P. Characterization and fine localization of two new genes in Xq28 using the genomic sequence/EST database screening approach. Genomics 34: 323-327, 1996. [PubMed: 8786131] [Full Text: https://doi.org/10.1006/geno.1996.0293]