Alternative titles; symbols
HGNC Approved Gene Symbol: ZNF75D
Cytogenetic location: Xq26.3 Genomic coordinates (GRCh38): X:135,248,589-135,344,109 (from NCBI)
Villa et al. (1992) reported the partial characterization of a novel zinc finger gene of the Kruppel type, which they designated ZNF75, mapping to the long arm of the X chromosome.
Villa et al. (1993) isolated a ZNF75 cDNA clone from a lung fibroblast cDNA library. The deduced 289-amino acid protein contains a 42-amino acid Kruppel-associated box (KRAB-B) encoded by exon 2 and 5 zinc finger motifs in tandem encoded by exon 3.
Villa et al. (1996) identified 3 additional members of the human ZNF75 family: ZNF75A (601473) and 2 pseudogenes, ZNF75B and ZNF75C. They identified homologs in great apes and confirmed that the ZNF75 family is highly conserved through evolution.
Villa et al. (1993) demonstrated that the ZNF75 gene has 3 exons.
Using a panel of somatic cell hybrids and in situ hybridization, Villa et al. (1992) mapped the ZNF75 gene to chromosome Xq26.
Villa et al. (1996) mapped several genes related to ZNF75: ZNF75A (601473) to chromosome 16pter-p11; ZNF75B, a pseudogene, to chromosome 12q13; and ZNF75C, a pseudogene, to chromosome 11.
Villa, A., Patrosso, C., Biunno, I., Frattini, A., Repetto, M., Mostardini, M., Evans, G., Susani, L., Strina, D., Redolfi, E., Lazzari, B., Pellegrini, M., Vezzoni, P. Isolation of a zinc finger motif (ZNF75) mapping on chromosome Xq26. Genomics 13: 1231-1236, 1992. [PubMed: 1505955] [Full Text: https://doi.org/10.1016/0888-7543(92)90040-y]
Villa, A., Strina, D., Frattini, A., Faranda, S., Macchi, P., Finelli, P., Bozzi, F., Susani, L., Archidiacono, N., Rocchi, M., Vezzoni, P. The ZNF75 zinc finger gene subfamily: isolation and mapping of the four members in humans and great apes. Genomics 35: 312-320, 1996. [PubMed: 8661144] [Full Text: https://doi.org/10.1006/geno.1996.0362]
Villa, A., Zucchi, I., Pilia, G., Strina, D., Susani, L., Morali, F., Patrosso, C., Frattini, A., Lucchini, F., Repetto, M., Sacco, M. G., Zoppe, M., Vezzoni, P. ZNF75: isolation of a cDNA clone of the KRAB zinc finger gene subfamily mapped in YACs 1 Mb telomeric of HPRT. Genomics 18: 223-229, 1993. [PubMed: 8288223] [Full Text: https://doi.org/10.1006/geno.1993.1459]