Entry - *430000 - INTERLEUKIN 3 RECEPTOR, Y-CHROMOSOMAL; IL3RA - OMIM

 
 
* 430000

INTERLEUKIN 3 RECEPTOR, Y-CHROMOSOMAL; IL3RA


Alternative titles; symbols

IL3RY
IL3RAY


HGNC Approved Gene Symbol: IL3RA

Cytogenetic location: Yp11.2     Genomic coordinates (GRCh38): Y:1,336,785-1,382,689 (from NCBI)


TEXT

▼ Description

The receptor for interleukin-3 (IL3; 147740) is a heterodimer that shares a beta chain (CSF2RB; 138981) in common with the receptors for IL5 (IL5R; 147851) and GMCSF (CSF2R; 306250), and, like these other cytokine receptors, has a ligand-specific alpha chain (IL3RA).

▼ Mapping

By fluorescence in situ hybridization, Kremer et al. (1993) demonstrated that the IL3RY gene is located in the pseudoautosomal region of the X and Y chromosomes. See 308385.


▼ REFERENCES

  1. Kremer, E., Baker, E., D'Andrea, R. J., Slim, R., Phillips, H., Moretti, P. A. B., Lopez, A. F., Petit, C., Vadas, M. A., Sutherland, G. R., Goodall, G. J. A cytokine receptor gene cluster in the X-Y pseudoautosomal region? Blood 82: 22-28, 1993. [PubMed: 8100720, related citations]


Creation Date:
Victor A. McKusick : 10/1/1993
Edit History:
terry : 08/26/2008
mgross : 9/6/2006
dkim : 7/2/1998
mark : 7/26/1995
mimadm : 3/11/1994
carol : 10/1/1993

* 430000

INTERLEUKIN 3 RECEPTOR, Y-CHROMOSOMAL; IL3RA


Alternative titles; symbols

IL3RY
IL3RAY


HGNC Approved Gene Symbol: IL3RA

Cytogenetic location: Yp11.2     Genomic coordinates (GRCh38): Y:1,336,785-1,382,689 (from NCBI)


TEXT

Description

The receptor for interleukin-3 (IL3; 147740) is a heterodimer that shares a beta chain (CSF2RB; 138981) in common with the receptors for IL5 (IL5R; 147851) and GMCSF (CSF2R; 306250), and, like these other cytokine receptors, has a ligand-specific alpha chain (IL3RA).

Mapping

By fluorescence in situ hybridization, Kremer et al. (1993) demonstrated that the IL3RY gene is located in the pseudoautosomal region of the X and Y chromosomes. See 308385.


REFERENCES

  1. Kremer, E., Baker, E., D'Andrea, R. J., Slim, R., Phillips, H., Moretti, P. A. B., Lopez, A. F., Petit, C., Vadas, M. A., Sutherland, G. R., Goodall, G. J. A cytokine receptor gene cluster in the X-Y pseudoautosomal region? Blood 82: 22-28, 1993. [PubMed: 8100720]


Creation Date:
Victor A. McKusick : 10/1/1993

Edit History:
terry : 08/26/2008
mgross : 9/6/2006
dkim : 7/2/1998
mark : 7/26/1995
mimadm : 3/11/1994
carol : 10/1/1993



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 4, 2024