Entry - 600149 - GLYCEROL KINASE 3 PSEUDOGENE; GK3P - OMIM

 
 
600149

GLYCEROL KINASE 3 PSEUDOGENE; GK3P


Alternative titles; symbols

GLYCEROL KINASE, TESTICULAR, TYPE B; GKTB
GKP3


HGNC Approved Gene Symbol: GK3


TEXT

▼ Cloning and Expression

Sargent et al. (1994) suggested that the human glycerol kinase gene family consists of at least 3 expressed loci. The GK gene (300474) on Xp21 is probably ancestral to several other genes which, because they are intronless, are suspected of having arisen by reverse transcriptase mediated events. These include 2 genes, GTKA (GK2; 600148) and GKTB, which are expressed as a single mRNA species in testis where expression is at a high level.


▼ Mapping

By fluorescence in situ hybridization, Sargent et al. (1994) mapped the testicular forms of GK to chromosome 4: GKTA to 4q13 and GKTB to 4q32.


▼ REFERENCES

  1. Sargent, C. A., Young, C., Marsh, S., Ferguson-Smith, M. A., Affara, N. A. The glycerol kinase gene family: structure of the Xp gene, and related intronless retroposons. Hum. Molec. Genet. 3: 1317-1324, 1994. [PubMed: 7987308, related citations] [Full Text]


Creation Date:
Victor A. McKusick : 10/18/1994
Edit History:
carol : 07/28/2015
carol : 7/28/2015
carol : 4/11/2013
carol : 2/8/1995
carol : 11/8/1994
terry : 10/18/1994

600149

GLYCEROL KINASE 3 PSEUDOGENE; GK3P


Alternative titles; symbols

GLYCEROL KINASE, TESTICULAR, TYPE B; GKTB
GKP3


HGNC Approved Gene Symbol: GK3


TEXT

Cloning and Expression

Sargent et al. (1994) suggested that the human glycerol kinase gene family consists of at least 3 expressed loci. The GK gene (300474) on Xp21 is probably ancestral to several other genes which, because they are intronless, are suspected of having arisen by reverse transcriptase mediated events. These include 2 genes, GTKA (GK2; 600148) and GKTB, which are expressed as a single mRNA species in testis where expression is at a high level.


Mapping

By fluorescence in situ hybridization, Sargent et al. (1994) mapped the testicular forms of GK to chromosome 4: GKTA to 4q13 and GKTB to 4q32.


REFERENCES

  1. Sargent, C. A., Young, C., Marsh, S., Ferguson-Smith, M. A., Affara, N. A. The glycerol kinase gene family: structure of the Xp gene, and related intronless retroposons. Hum. Molec. Genet. 3: 1317-1324, 1994. [PubMed: 7987308] [Full Text: https://doi.org/10.1093/hmg/3.8.1317]


Creation Date:
Victor A. McKusick : 10/18/1994

Edit History:
carol : 07/28/2015
carol : 7/28/2015
carol : 4/11/2013
carol : 2/8/1995
carol : 11/8/1994
terry : 10/18/1994



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 5, 2024