Entry - %600318 - TYPE 1 DIABETES MELLITUS 3; T1D3 - OMIM

 
ICD+
% 600318

TYPE 1 DIABETES MELLITUS 3; T1D3


Alternative titles; symbols

DIABETES MELLITUS, INSULIN-DEPENDENT, 3; IDDM3
INSULIN-DEPENDENT DIABETES MELLITUS 3


Cytogenetic location: 15q26     Genomic coordinates (GRCh38): 15:88,500,001-101,991,189


Gene-Phenotype Relationships
Location Phenotype Phenotype
MIM number 		Inheritance Phenotype
mapping key
15q26 {Diabetes mellitus, insulin-dependent, 3} 600318 2

▼ TEXT

For a general phenotypic description of type 1 diabetes mellitus, see T1D (222100).

▼ Mapping

To identify novel loci predisposing to insulin-dependent diabetes mellitus, Field et al. (1994) studied 250 families with more than one diabetic child. Affected sib-pair linkage analysis revealed strong evidence for an IDDM susceptibility locus near D15S107 on chromosome 15q26. Field et al. (1994) designated the locus IDDM3. In an independent study, Luo et al. (1995) confirmed linkage to 15q.


▼ REFERENCES

  1. Field, L. L., Tobias, R., Magnus, T. A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus. Nature Genet. 8: 189-194, 1994. [PubMed: 7842018, related citations] [Full Text]

  2. Luo, D.-F., Bui, M. M., Muir, A., Maclaren, N. K., Thomson, G., She, J.-X. Affected sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27. Am. J. Hum. Genet. 57: 911-919, 1995. [PubMed: 7573053, related citations]


Creation Date:
Victor A. McKusick : 1/20/1995
Edit History:
carol : 09/04/2020
carol : 03/21/2012
joanna : 3/18/2004
mark : 8/19/1997
jamie : 1/29/1997
mark : 10/19/1995
mimadm : 9/23/1995
carol : 1/20/1995

% 600318

TYPE 1 DIABETES MELLITUS 3; T1D3


Alternative titles; symbols

DIABETES MELLITUS, INSULIN-DEPENDENT, 3; IDDM3
INSULIN-DEPENDENT DIABETES MELLITUS 3


DO: 0110742;  


Cytogenetic location: 15q26     Genomic coordinates (GRCh38): 15:88,500,001-101,991,189


Gene-Phenotype Relationships

Location Phenotype Phenotype
MIM number 		Inheritance Phenotype
mapping key
15q26 {Diabetes mellitus, insulin-dependent, 3} 600318 2

TEXT

For a general phenotypic description of type 1 diabetes mellitus, see T1D (222100).

Mapping

To identify novel loci predisposing to insulin-dependent diabetes mellitus, Field et al. (1994) studied 250 families with more than one diabetic child. Affected sib-pair linkage analysis revealed strong evidence for an IDDM susceptibility locus near D15S107 on chromosome 15q26. Field et al. (1994) designated the locus IDDM3. In an independent study, Luo et al. (1995) confirmed linkage to 15q.


REFERENCES

  1. Field, L. L., Tobias, R., Magnus, T. A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus. Nature Genet. 8: 189-194, 1994. [PubMed: 7842018] [Full Text: https://doi.org/10.1038/ng1094-189]

  2. Luo, D.-F., Bui, M. M., Muir, A., Maclaren, N. K., Thomson, G., She, J.-X. Affected sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27. Am. J. Hum. Genet. 57: 911-919, 1995. [PubMed: 7573053]


Creation Date:
Victor A. McKusick : 1/20/1995

Edit History:
carol : 09/04/2020
carol : 03/21/2012
joanna : 3/18/2004
mark : 8/19/1997
jamie : 1/29/1997
mark : 10/19/1995
mimadm : 9/23/1995
carol : 1/20/1995



NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 7, 2024