Entry - *601909 - G PROTEIN-COUPLED RECEPTOR 21; GPR21 - OMIM

 
 
* 601909

G PROTEIN-COUPLED RECEPTOR 21; GPR21


HGNC Approved Gene Symbol: GPR21

Cytogenetic location: 9q33.2     Genomic coordinates (GRCh38): 9:123,033,667-123,049,103 (from NCBI)


TEXT

▼ Cloning and Expression

O'Dowd et al. (1997) isolated 4 novel human putative G protein-coupled receptor (GPCR) genes: GPR20 (601908), GPR21, GPR22 (601910), and GPR23 (LPAR4; 300086). All 4 contain the 7 putative transmembrane regions characteristic of GPCRs. Their deduced proteins share significant sequence identity to each other and to other members of the GPCR family.


▼ Mapping

O'Dowd et al. (1997) mapped the GPR21 gene to chromosome 9q33 by fluorescence in situ hybridization.


▼ REFERENCES

  1. O'Dowd, B. F., Nguyen, T., Jung, B. P., Marchese, A., Cheng, R., Heng, H. H. Q., Kolakowski, L. F., Jr., Lynch, K. R., George, S. R. Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes. Gene 187: 75-81, 1997. [PubMed: 9073069, related citations] [Full Text]


Creation Date:
Victor A. McKusick : 6/27/1997
Edit History:
carol : 04/14/2014
mark : 6/27/1997

* 601909

G PROTEIN-COUPLED RECEPTOR 21; GPR21


HGNC Approved Gene Symbol: GPR21

Cytogenetic location: 9q33.2     Genomic coordinates (GRCh38): 9:123,033,667-123,049,103 (from NCBI)


TEXT

Cloning and Expression

O'Dowd et al. (1997) isolated 4 novel human putative G protein-coupled receptor (GPCR) genes: GPR20 (601908), GPR21, GPR22 (601910), and GPR23 (LPAR4; 300086). All 4 contain the 7 putative transmembrane regions characteristic of GPCRs. Their deduced proteins share significant sequence identity to each other and to other members of the GPCR family.


Mapping

O'Dowd et al. (1997) mapped the GPR21 gene to chromosome 9q33 by fluorescence in situ hybridization.


REFERENCES

  1. O'Dowd, B. F., Nguyen, T., Jung, B. P., Marchese, A., Cheng, R., Heng, H. H. Q., Kolakowski, L. F., Jr., Lynch, K. R., George, S. R. Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes. Gene 187: 75-81, 1997. [PubMed: 9073069] [Full Text: https://doi.org/10.1016/s0378-1119(96)00722-6]


Creation Date:
Victor A. McKusick : 6/27/1997

Edit History:
carol : 04/14/2014
mark : 6/27/1997



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 4, 2024