Entry - *602246 - ZINC FINGER PROTEIN 193; ZNF193 - OMIM

 
 
* 602246

ZINC FINGER PROTEIN 193; ZNF193


HGNC Approved Gene Symbol: ZSCAN9

Cytogenetic location: 6p22.1     Genomic coordinates (GRCh38): 6:28,225,240-28,233,487 (from NCBI)


TEXT

▼ Cloning and Expression

Lee et al. (1997) cloned ZNF193 from an intestinal cDNA library. Northern blot analysis revealed that a 1.6-kb mRNA is expressed strongly in testis. Three larger mRNAs were detected at lower levels in other tissues. ZNF193 belongs to a subfamily of Kruppel proteins that have a 67-amino acid SCAN box and lack the A and B domains of the Kruppel-associated box (KRAB).


▼ Mapping

By direct cDNA hybridization to YACs from region 6p21.3, Lee et al. (1997) isolated ZNF193 from a cluster of zinc finger protein genes. All were members of the Kruppel family of transcriptional activators, containing a conserved C2H2 domain (see 165230).


▼ REFERENCES

  1. Lee, P. L., Gelbart, T., West, C., Adams, M., Blackstone, R., Beutler, E. Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. Genomics 43: 191-201, 1997. [PubMed: 9244436, related citations] [Full Text]


Creation Date:
Rebekah S. Rasooly : 1/8/1998
Edit History:
alopez : 11/16/2010
terry : 8/19/1998
alopez : 1/28/1998
alopez : 1/14/1998
alopez : 1/9/1998

* 602246

ZINC FINGER PROTEIN 193; ZNF193


HGNC Approved Gene Symbol: ZSCAN9

Cytogenetic location: 6p22.1     Genomic coordinates (GRCh38): 6:28,225,240-28,233,487 (from NCBI)


TEXT

Cloning and Expression

Lee et al. (1997) cloned ZNF193 from an intestinal cDNA library. Northern blot analysis revealed that a 1.6-kb mRNA is expressed strongly in testis. Three larger mRNAs were detected at lower levels in other tissues. ZNF193 belongs to a subfamily of Kruppel proteins that have a 67-amino acid SCAN box and lack the A and B domains of the Kruppel-associated box (KRAB).


Mapping

By direct cDNA hybridization to YACs from region 6p21.3, Lee et al. (1997) isolated ZNF193 from a cluster of zinc finger protein genes. All were members of the Kruppel family of transcriptional activators, containing a conserved C2H2 domain (see 165230).


REFERENCES

  1. Lee, P. L., Gelbart, T., West, C., Adams, M., Blackstone, R., Beutler, E. Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. Genomics 43: 191-201, 1997. [PubMed: 9244436] [Full Text: https://doi.org/10.1006/geno.1997.4806]


Creation Date:
Rebekah S. Rasooly : 1/8/1998

Edit History:
alopez : 11/16/2010
terry : 8/19/1998
alopez : 1/28/1998
alopez : 1/14/1998
alopez : 1/9/1998



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: April 29, 2024