Entry - *602277 - ZINC FINGER PROTEIN 184; ZNF184 - OMIM

 
 
* 602277

ZINC FINGER PROTEIN 184; ZNF184


HGNC Approved Gene Symbol: ZNF184

Cytogenetic location: 6p22.1     Genomic coordinates (GRCh38): 6:27,404,006-27,473,105 (from NCBI)


TEXT

▼ Cloning and Expression

By exon trapping using YAC contigs spanning the 6p21.3 region, which contains a cluster of zinc finger protein genes, Goldwurm et al. (1997) isolated a partial cDNA, designated ZNF184, from a placental library. Sequence analysis indicated that ZNF184 is a classic Kruppel zinc finger gene with a conserved C2H2 domain at the C terminus and Kruppel-associated boxes (KRAB) A and B at the N terminus. Northern blot analysis revealed expression of ZNF184 as a 3.2-kb transcript in all tissues analyzed, with predominant expression in testis.


▼ REFERENCES

  1. Goldwurm, S., Menzies, M. L., Banyer, J. L., Powell, B. L. W., Jazwinska, E. C. Identification of a novel Krueppel-related zinc finger gene (ZNF184) mapping to 6p21.3. Genomics 40: 486-489, 1997. [PubMed: 9073517, related citations] [Full Text]


Creation Date:
Rebekah S. Rasooly : 1/26/1998
Edit History:
alopez : 11/16/2010
alopez : 2/2/1998
carol : 1/28/1998

* 602277

ZINC FINGER PROTEIN 184; ZNF184


HGNC Approved Gene Symbol: ZNF184

Cytogenetic location: 6p22.1     Genomic coordinates (GRCh38): 6:27,404,006-27,473,105 (from NCBI)


TEXT

Cloning and Expression

By exon trapping using YAC contigs spanning the 6p21.3 region, which contains a cluster of zinc finger protein genes, Goldwurm et al. (1997) isolated a partial cDNA, designated ZNF184, from a placental library. Sequence analysis indicated that ZNF184 is a classic Kruppel zinc finger gene with a conserved C2H2 domain at the C terminus and Kruppel-associated boxes (KRAB) A and B at the N terminus. Northern blot analysis revealed expression of ZNF184 as a 3.2-kb transcript in all tissues analyzed, with predominant expression in testis.


REFERENCES

  1. Goldwurm, S., Menzies, M. L., Banyer, J. L., Powell, B. L. W., Jazwinska, E. C. Identification of a novel Krueppel-related zinc finger gene (ZNF184) mapping to 6p21.3. Genomics 40: 486-489, 1997. [PubMed: 9073517] [Full Text: https://doi.org/10.1006/geno.1996.4583]


Creation Date:
Rebekah S. Rasooly : 1/26/1998

Edit History:
alopez : 11/16/2010
alopez : 2/2/1998
carol : 1/28/1998



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 3, 2024