Entry - *602787 - HISTONE GENE CLUSTER 1, H2A HISTONE FAMILY, MEMBER I; HIST1H2AI - OMIM

 
 
* 602787

HISTONE GENE CLUSTER 1, H2A HISTONE FAMILY, MEMBER I; HIST1H2AI


Alternative titles; symbols

HISTONE GENE CLUSTER 1, H2AI
HIST1 CLUSTER, H2AI
H2A HISTONE FAMILY, MEMBER C; H2AFC
H2A/C


HGNC Approved Gene Symbol: H2AC13

Cytogenetic location: 6p22.1     Genomic coordinates (GRCh38): 6:27,808,173-27,808,667 (from NCBI)


▼ TEXT

For background information on histones, histone gene clusters, and the H2A histone family, see HIST1H2AA (613499).

▼ Mapping

By analysis of a YAC contig from chromosome 6p22-p21.3, Albig and Doenecke (1997) characterized a second cluster of 16 histone genes, including H2A/c, located 2 Mb centromeric to the major histone gene cluster.

By genomic sequence analysis, Marzluff et al. (2002) determined that the histone gene cluster on chromosome 6p22-p21, which they called histone gene cluster-1 (HIST1), contains 55 histone genes, including HIST1H2AI.


▼ Gene Function

See HIST1H2AA (613499) for functional information on H2A histones.

▼ REFERENCES

  1. Albig, W., Doenecke, D. The human histone gene cluster at the D6S105 locus. Hum. Genet. 101: 284-294, 1997. [PubMed: 9439656, related citations] [Full Text]

  2. Marzluff, W. F., Gongidi, P., Woods, K. R., Jin, J., Maltais, L. J. The human and mouse replication-dependent histone genes. Genomics 80: 487-498, 2002. [PubMed: 12408966, related citations] [Full Text]


Contributors:
Matthew B. Gross - updated : 01/11/2013
Creation Date:
Rebekah S. Rasooly : 7/9/1998
Edit History:
mgross : 01/11/2013
mgross : 7/19/2010
tkritzer : 4/3/2003
alopez : 8/26/1998
alopez : 7/14/1998
alopez : 7/9/1998

* 602787

HISTONE GENE CLUSTER 1, H2A HISTONE FAMILY, MEMBER I; HIST1H2AI


Alternative titles; symbols

HISTONE GENE CLUSTER 1, H2AI
HIST1 CLUSTER, H2AI
H2A HISTONE FAMILY, MEMBER C; H2AFC
H2A/C


HGNC Approved Gene Symbol: H2AC13

Cytogenetic location: 6p22.1     Genomic coordinates (GRCh38): 6:27,808,173-27,808,667 (from NCBI)


TEXT

For background information on histones, histone gene clusters, and the H2A histone family, see HIST1H2AA (613499).

Mapping

By analysis of a YAC contig from chromosome 6p22-p21.3, Albig and Doenecke (1997) characterized a second cluster of 16 histone genes, including H2A/c, located 2 Mb centromeric to the major histone gene cluster.

By genomic sequence analysis, Marzluff et al. (2002) determined that the histone gene cluster on chromosome 6p22-p21, which they called histone gene cluster-1 (HIST1), contains 55 histone genes, including HIST1H2AI.


Gene Function

See HIST1H2AA (613499) for functional information on H2A histones.

REFERENCES

  1. Albig, W., Doenecke, D. The human histone gene cluster at the D6S105 locus. Hum. Genet. 101: 284-294, 1997. [PubMed: 9439656] [Full Text: https://doi.org/10.1007/s004390050630]

  2. Marzluff, W. F., Gongidi, P., Woods, K. R., Jin, J., Maltais, L. J. The human and mouse replication-dependent histone genes. Genomics 80: 487-498, 2002. [PubMed: 12408966] [Full Text: https://linkinghub.elsevier.com/retrieve/pii/S0888754302968503]


Contributors:
Matthew B. Gross - updated : 01/11/2013

Creation Date:
Rebekah S. Rasooly : 7/9/1998

Edit History:
mgross : 01/11/2013
mgross : 7/19/2010
tkritzer : 4/3/2003
alopez : 8/26/1998
alopez : 7/14/1998
alopez : 7/9/1998



NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: April 29, 2024