Alternative titles; symbols
HGNC Approved Gene Symbol: H2AC16
Cytogenetic location: 6p22.1 Genomic coordinates (GRCh38): 6:27,865,317-27,865,798 (from NCBI)
For background information on histones, histone gene clusters, and the H2A histone family, see HIST1H2AA (613499).
Albig et al. (1997) identified a gene encoding a member of the H2A class of histones and designated it H2A/i.
By analysis of a YAC contig from chromosome 6p22-p21.3, Albig and Doenecke (1997) characterized a second cluster of 16 histone genes, including H2A/i, located 2 Mb centromeric to the major histone gene cluster.
By genomic sequence analysis, Marzluff et al. (2002) determined that the histone gene cluster on chromosome 6p22-p21, which they called histone gene cluster-1 (HIST1), contains 55 histone genes, including HIST1H2AL.
See HIST1H2AA (613499) for functional information on H2A histones.
Albig, W., Doenecke, D. The human histone gene cluster at the D6S105 locus. Hum. Genet. 101: 284-294, 1997. [PubMed: 9439656] [Full Text: https://doi.org/10.1007/s004390050630]
Albig, W., Meergans, T., Doenecke, D. Characterization of the H1.5 gene completes the set of human H1 subtype genes. Gene 184: 141-148, 1997. [PubMed: 9031620] [Full Text: https://doi.org/10.1016/s0378-1119(96)00582-3]
Marzluff, W. F., Gongidi, P., Woods, K. R., Jin, J., Maltais, L. J. The human and mouse replication-dependent histone genes. Genomics 80: 487-498, 2002. [PubMed: 12408966] [Full Text: https://linkinghub.elsevier.com/retrieve/pii/S0888754302968503]