Entry - *602802 - HISTONE GENE CLUSTER 1, H2B HISTONE FAMILY, MEMBER M; HIST1H2BM - OMIM

 
 
* 602802

HISTONE GENE CLUSTER 1, H2B HISTONE FAMILY, MEMBER M; HIST1H2BM


Alternative titles; symbols

HISTONE GENE CLUSTER 1, H2BM
HIST1 CLUSTER, H2BM
H2B HISTONE FAMILY, MEMBER E; H2BFE
H2B/E


HGNC Approved Gene Symbol: H2BC14

Cytogenetic location: 6p22.1     Genomic coordinates (GRCh38): 6:27,815,022-27,815,489 (from NCBI)


▼ TEXT

For background information on histones, histone gene clusters, and the H2B histone family, see HIST1H2BA (609904).

▼ Mapping

By analysis of a YAC contig from chromosome 6p22-p21.3, Albig and Doenecke (1997) characterized a second cluster of 16 histone genes, including H2B/e, located 2 Mb centromeric to the major histone gene cluster.

By genomic sequence analysis, Marzluff et al. (2002) determined that the histone gene cluster on chromosome 6p22-p21, which they called histone gene cluster-1 (HIST1), contains 55 histone genes, including HIST1H2BM.


▼ Gene Function

See HIST1H2BA (609904) for functional information on H2B histones.

▼ REFERENCES

  1. Albig, W., Doenecke, D. The human histone gene cluster at the D6S105 locus. Hum. Genet. 101: 284-294, 1997. [PubMed: 9439656, related citations] [Full Text]

  2. Marzluff, W. F., Gongidi, P., Woods, K. R., Jin, J., Maltais, L. J. The human and mouse replication-dependent histone genes. Genomics 80: 487-498, 2002. [PubMed: 12408966, related citations] [Full Text]


Contributors:
Matthew B. Gross - updated : 01/29/2013
Creation Date:
Rebekah S. Rasooly : 7/9/1998
Edit History:
mgross : 01/29/2013
mgross : 7/22/2010
tkritzer : 3/31/2003
alopez : 8/26/1998
alopez : 7/14/1998
alopez : 7/9/1998

* 602802

HISTONE GENE CLUSTER 1, H2B HISTONE FAMILY, MEMBER M; HIST1H2BM


Alternative titles; symbols

HISTONE GENE CLUSTER 1, H2BM
HIST1 CLUSTER, H2BM
H2B HISTONE FAMILY, MEMBER E; H2BFE
H2B/E


HGNC Approved Gene Symbol: H2BC14

Cytogenetic location: 6p22.1     Genomic coordinates (GRCh38): 6:27,815,022-27,815,489 (from NCBI)


TEXT

For background information on histones, histone gene clusters, and the H2B histone family, see HIST1H2BA (609904).

Mapping

By analysis of a YAC contig from chromosome 6p22-p21.3, Albig and Doenecke (1997) characterized a second cluster of 16 histone genes, including H2B/e, located 2 Mb centromeric to the major histone gene cluster.

By genomic sequence analysis, Marzluff et al. (2002) determined that the histone gene cluster on chromosome 6p22-p21, which they called histone gene cluster-1 (HIST1), contains 55 histone genes, including HIST1H2BM.


Gene Function

See HIST1H2BA (609904) for functional information on H2B histones.

REFERENCES

  1. Albig, W., Doenecke, D. The human histone gene cluster at the D6S105 locus. Hum. Genet. 101: 284-294, 1997. [PubMed: 9439656] [Full Text: https://doi.org/10.1007/s004390050630]

  2. Marzluff, W. F., Gongidi, P., Woods, K. R., Jin, J., Maltais, L. J. The human and mouse replication-dependent histone genes. Genomics 80: 487-498, 2002. [PubMed: 12408966] [Full Text: https://linkinghub.elsevier.com/retrieve/pii/S0888754302968503]


Contributors:
Matthew B. Gross - updated : 01/29/2013

Creation Date:
Rebekah S. Rasooly : 7/9/1998

Edit History:
mgross : 01/29/2013
mgross : 7/22/2010
tkritzer : 3/31/2003
alopez : 8/26/1998
alopez : 7/14/1998
alopez : 7/9/1998



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 6, 2024