Рис. F c seq
Нуклеотидная и аминокислотная последовательности
гена протеина C
gaccctcaattccagcttccgcctgacggcca
gcacacagggacagccctttcattccgcttccacctgggggtgcaggcagagcagcagc
gggggtagcactgcccggagctcagaagtcctcctcagacaggtgccagtgcctccaga
-42
atg tgg cag ctc aca agc ctc ctg ctg ttc gtg gcc acc tgg gga
met trp gln leu thr ser leu leu leu phe val ala thr trp gly 15
att tcc ggc aca cca gct cct ctt gac tca gtg ttc tcc agc agc
ile ser gly thr pro ala pro leu asp ser val phe ser ser ser 30
-1 +1
gag cgt gcc cac cag gtg ctg cgg atc cgc aaa cgt gcc aac tcc
glu arg ala his gln val leu arg ile arg lys arg ala asn ser 45
ttc ctg gag gag ctc cgt cac agc agc ctg gag cgg gag tgc ata
phe leu glu gly leu arg his ser ser leu glu arg glu cys ile 60
gag gag atc tgt gac ttc gag gag gcc aag gaa att ttc caa aat
glu glu ile cys asp phe glu glu ala lys glu ile phe gln asn 75
gtg gat gac aca ctg gcc ttc tgg tcc aag cac gtc gac ggt gac
val asp asp thr leu ala phe trp ser lys his val asp gly asp 90
cag tgc ttg gtc ttg ccc ttg gag cac ccg tgc gcc agc ctg tgc
gln cys leu val leu pro leu glu his pro cys ala ser leu cys 105
tgc ggg cac ggc acg tgc atc gac ggc atc ggc agc ttc agc tgc
cys gly his gly yjt cys ile asp gly ile gly ser phe ser cys 120
gac tgc cgc agc ggc tgg gag ggc cgc ttc tgc cag cgc gag gtg
asp cys arg ser gly trp glu gly arg phe cys gln arg glu val 135
agc ttc ctc aat tgc tct ctg gac aac ggc ggc tgc acg cat tac
ser phe leu asn cys ser leu asp asn gly gly cys thr his tyr 150
tgc cta gag gag gtg ggc tgg cgg cgc tgt agc tgt gcg cct ggc
cys leu glu glu val gly trp arg arg cys ser cys ala pro gly 165
tac aag ctg ggg gac gac ctc ctg cag tgt cac ccc gca gtg aag
tyr lys leu gly asl asp leu leu gln cys his pro ala val lys 180
ttc cct tgt ggg agg ccc tgg aag cgg atg gag aag aag cgc agt
phe pro cys gly arg pro trp lys arg met glu lys lys arg ser 195
cac ctg aaa cga gac aca gaa gac caa gaa gac caa gta gat ccg
his leu lys arg asp thr glu asp gln glu asp gln val asp pro 210
cgg ctc att gat ggg aag atg acc agg cgg gga gac agc ccc tgg
arg leu ile asp gly lys met thr arg arg gly asp ser pro trp 225
cag gtg gtc ctg ctg gac tca aag aag aag ctg gcc tgc ggg gca
gln val val leu leu asp ser lys lys lys leu ala cys gly ala 240
gtg ctc atc cac ccc tcc tgg gtg ctg aca gcg gcc cac tgc atg
val leu ile his pro ser trp val leu thr ala ala his cys met 255
gat gag tcc aag aag ctc ctt gtc agg ctt gga gag tat gac ctg
asp glu ser lys lys leu leu val arg leu gly glu tyr asp leu 270
cgg cgc tgg gag aag tgg gag ctg gac ctg gac atc aag gag gtc
arg arg trp glu lys trp glu leu asp leu asp ile lys glu val 285
ttc gtc cac ccc aac tac agc aag agc acc acc gac aat gac atc
phe val his pro asn tyr ser lys ser thr thr asp asn asp ile 300
gca ctg ctg cac ctg gcc cag ccc gcc acc ctc tcg cag acc ata
ala leu leu his leu ala gln pro ala thr leu ser gln thr ile 315
gtg ccc atc tgc ctc ccg gac agc ggc ctt gca gag cgc gag ctc
val pro ile cys leu pro asp ser gly leu ala glu arg glu leu 330
aat cag gcc ggc cag gag acc ctc gtg acg ggc tgg ggc tac cac
asn gln ala gly gln glu thr leu val thr gly trp gly tyr his 345
agc agc cga gag aag gag gcc aag aga aac cgc acc ttc gtc ctc
ser ser arg glu lys glu ala lys arg asn arg thr phe val leu 360
aac ttc atc aag att ccc gtg gtc ccg cac aat gag tgc agc gag
asn phe ile lys ile pro val val pro his asn glu cys ser glu 375
gtc atg agc aac atg gtg tct gag aac atg ctg tgt gcg ggc atc
val met ser asn met val ser glu asn met leu cys ala gly ile 390
ctc ggg gac cgg cag gat gcc tgc gag ggc gac agt ggg ggg ccc
leu gly asp arg gln asp ala cys gu gly asp ser gly gly pro 405
atg gtc gcc tcc ttc cac ggc acc tgg ttc ctg gtg ggc ctg gtg
met val ala ser phe his gly thr trp phe leu val gly leu val 420
agc tgg ggt gag ggc tgt ggg ctc ctt cac aac tac ggc gtt tac
ser trp gly glu gly cys gly leu leu his asn tyr gly val tyr 435
acc aaa gtc agc cgc tac ctc gac tgg atc cat ggg cac atc aga
thr lys val ser arg tyr leu asp trp ile his gly his ile arg 450
gac aag gaa gcc ccc cag aag agc tgg gca cct tag cgaccctccct
asp lys glu ala pro gln lys ser trp ala pro ter
gcagggctgggcttttgcatggcaatggatgggacattaaagggacatgtaacaagcac
accggcctgctgttctgtccttccatccctcttttgggctcttctggagggaagtaaca
tttactgagcacctgttgtatgtcacatgccttatgaatagaatcttaactcctagagc
aactctgtggggtggggaggagcagatccaagttttgcggggtctaaagctgtgtgtgt
tgagggggatactctgtttatgaaaaagaataaaaaacacaaccacgaagccactagag
ccttttccagggctttgggaagagcctgtgcaagccggggatgctgaaggtgaggcttg
accagctttccagctagcccagctatgaggtagacatgtttagctcatatcacagagga
ggaaactgaggggtctgaaaggtttacatggtggagccaggattcaaatctaggtctga
ctccaaaacccaggtgcttttttctgttctccactgtcctggaggacagctgtttcgac
ggtgctcagtgtggaggccactattagctctgtagggaagcagccagagacccagaaag
tgttggttcagcccagaat
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