Рис. G6PD seq
Нуклеотидная и аминокислотная последовательности
гена глюкозо-6 фосфат дегидрогеназы (G6PD)человека
gcgcagacagcgtc
atg gca gag cag gtg gcc ctg agc cgg acc cac gtg tgc ggg atc
met ala glu gln val ala leu ser arg thr his val cys gly ile 15
ctg cgg gaa gag ctt ttc cag ggc gat gcc ttc cat cag tcg gat
leu arg glu glu leu phe gln gly asp ala phe his gln ser asp 30
+1
aca cac ata ttc atc atc atg ggt gca tcg ggt gac ctg gcc aag
thr his ile phe ile ile met gly ala ser gly asp leu ala lys 45
aag aag atc tac ccc acc atc tgg tgg ctg ttc cgg gat ggc ctt
lys lys ile tyr pro thr ile trp trp leu phe arg asp gly leu 60
ctg ccc gaa aac acc ttc atc gtg ggc tat gcc cgt tcc cgc ctc
leu pro glu asn thr phe ile val gly tyr ala arg ser arg leu 75
aca gtg gct gac atc cgc aaa cag agt gag ccc ttc ttc aag gcc
thr val ala asp ile arg lys gln ser glu pro phe phe lys ala 90
acc cca gag gag aag ctc aag ctg gag gac ttc ttt gcc cgc aac
thr pro glu glu lys leu lys leu glu asp phe phe ala arg asn 105
tcc tat gtg gct ggc cag tac gat gat gca gcc tcc tac cag cgc
ser tyr val ala gly gln tyr asp asp ala ala ser tyr gln arg 120
ctc aac agc cac atg aat gcc ctc cac ctg ggg tca cag gcc aac
leu asn ser his met asn ala leu his leu gly ser gln ala asn 135
cgc ctc ttc tac ctg gcc ttg ccc ccg acc gtc tac gag gcc gtc
arg leu phe tyr leu ala leu pro pro thr val tyr glu ala val 150
acc aag aac att cac gag tcc tgc atg agc cag ata ggc tgg aac
thr lys asn ile his glu ser cys met ser gln ile gly trp asn 165
cgc atc atc gtg gag aag ccc ttc ggg agg gac ctg cag agc tct
arg ile ile val glu lys pro phe gly arg asp leu gln ser ser 180
gac cgg ctg tcc aac cac atc tcc tcc ctg ttc cgt gag gac cag
asp arg leu ser asn his ile ser ser leu phe arg glu asp gln 195
atc tac cgc atc gac cac tac ctg ggc aag gag atg gtg cag aac
ile tyr arg ile asp his tyr leu gly lys glu met val gln asn 210
ctc atg gtg ctg aga ttt gcc aac agg atc ttc ggc ccc atc tgg
leu met val leu arg phe ala asn arg ile phe gly pro ile trp 225
aac cgg gac aac atc gcc tgc gtt atc ctc acc ttc aag gag ccc
asn arg asp asn ile ala cys val ile leu thr phe lys glu pro 240
ttt ggc act gag ggt cgc ggg ggc tat ttc gat gaa ttt ggg atc
phe gly thr glu gly arg gly gly tyr phe asp glu phe gly ile 255
atc cgg gac gtg atg cag aac cac cta ctg cag atg ctg tgt ctg
ile arg asp val met gln asn his leu leu gln met leu cys leu 270
gtg gcc atg gag aag ccc gcc tcc acc aac tca gat gac gtc cgt
val ala met glu lys pro ala ser thr asn ser asp asp val arg 285
gat gag aag gtc aag gtg ttg aaa tgc atc tca gag gtg cag gcc
asp glu lys val lys val leu lys cys ile ser glu val gln ala 300
aac aat gtg gtc ctg ggc cag tac gtg ggg aac ccc gat gga gag
asn asn val val leu gly gln tyr val gly asn pro asp gly glu 315
ggc gag gcc acc aaa ggg tac ctg gac gac ccc acg gtg ccc cgc
gly glu ala thr lys gly tyr leu asp asp pro thr val pro arg 330
ggg tcc acc acc gcc act ttt gca gcc gtc gtc ctc tat gtg gag
gly ser thr thr ala thr phe ala ala val val leu tyr val glu 345
aat gag agg tgg gat ggg gtg ccc ttc atc ctg cgc tgc ggc aag
asn glu arg trp asp gly val pro phe ile leu arg cys gly lys 360
gcc ctg aac gag cgc aag gcc gag gtg agg ctg cag ttc cat gat
ala leu asn glu arg lys ala glu val arg leu gln phe his asp 375
gtg gcc ggc gac atc ttc cac cag cag tgc aag cgc aac gag ctg
val ala gly asp ile phe his gln gln cys lys arg asn glu leu 390
gtg atc cgc gtg cag ccc aac gag gcc gtg tac acc aag atg atg
val ile arg val gln pro asn glu ala val tyr thr lys met met 405
acc aag aag ccg ggc atg ttc ttc aac ccc gag gag tcg gag ctg
thr lys lys pro gly met phe phe asn pro glu glu ser glu leu 420
gac ctg acc tac ggc aac aga tac aag aac gtg aag ctc cct gac
asp leu thr tyr gly asn arg tyr lys asn val lys leu pro asp 435
gcc tac gag cgc ctc atc ctg gac gtc ttc tgc ggg agc cag atg
ala tyr glu arg leu ile leu asp val phe cys gly ser gln met 450
cac ttc gtg cgc agc gac gag ctc cgt gag gcc tgg cgt att ttc
his phe val arg ser asp glu leu arg glu ala trp arg ile phe 465
acc cca ctg ctg cac cag att gag ctg gag aag ccc aag ccc atc
thr pro leu leu his gln ile glu leu glu lys pro lys pro ile 480
ccc tat att tat ggc agc cga ggc ccc acg gag gca gac gag ctg
pro tyr ile tyr gly ser arg gly pro thr glu ala asp glu leu 495
atg aag aga gtg ggt ttc cag tat gag ggc acc tac aag tgg gtg
met lys arg val gly phe gln tyr glu gly thr tyr lys trp val 510
aac ccc cac aag ctc tga gccctgggcacccacctccacccccgccacggcca
asn pro his lys leu ter
ccctccttcccgccgcccgaccccgagtcgggaggactccgggaccattgacctcagct
gcacattcctggccccgggctctggccacctggccgcccctcgctgctgctactacccg
agcccagctacattcctcagctgccaagcactcgagaccatcttggcccctccagaccc
tgcctgagcctaggagcttgagtcacctcctccactcactccagcccaacagaaggaag
gaggagggcgcccattcgtctgtcccagagcttattggccactgggtctcgctccgagt
ggggccagggtgggagggagggtcagggggaggaaaggggcgagcacccacgtgagaga
atctgcctgtggccttgcccgccagcctcagtgccacttgacattccttgtcaccagca
acatctcgagccccctggatgtcccctgtcccaccaactctgcactccatggccacccc
gtgccacccgtaggcagcctctctgctataagaaaagcagacgcagcagctgggacccc
tcccaacctcaatgccctgccattaaatccgcaaacagc
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