Рис. F 10 seq
Нуклеотидная и аминокислотная последовательности
гена фaктора X (Factor X) человека
-40
ATG GGG CGC CCA CTG CAC CTC GTC CTG CTC AGT GCC TCC CTG GCT
met gly arg pro leu his leu val leu leu ser ala ser leu ala 15
GGC CTC CTG CTG CTC GGG GAA AGT CTG TTC ATC CGC AGG GAG CAG
gly leu leu leu leu gly glu ser leu phe ile arg arg glu gln 30
-1 +1
GCC AAC AAC ATC CTG GCG AGG GTC ACG AGG GCC AAT TCC TTT CTT
ala asn asn ile leu ala arg val thr arg ala asn ser phe leu 45
GAA GAG ATG AAG AAA GGA CAC CTC GAA AGA GAG TGC ATG GAA GAG
glu glu met lys lys gly his leu glu arg glu cys met glu glu 60
ACC TGC TCA TAC GAA GAG GCC CGC GAG GTC TTT GAG GAC AGC GAC
thr cys ser tyr glu glu ala arg glu val phe glu asp ser asp 75
AAG ACG AAT GAA TTC TGG AAT AAA TAC AAA GAT GGC GAC CAG TGT
lys thr asn glu phe trp asn lys tyr lys asp gly asp gln cys 90
GAG ACC AGT CCT TGC CAG AAC CAG GGC AAA TGT AAA GAC GGC CTC
glu thr ser pro cys gln asn gln gly lys cys lys asp gly leu 105
GGG GAA TAC ACC TGC ACC TGT TTA GAA GGA TTC GAA GGC AAA AAC
gly glu tyr thr cys thr cys leu glu gly phe glu gly lys asn 120
TGT GAA TTA TTC ACA CGG AAG CTC TGC AGC CTG GAC AAC GGG GAC
cys glu leu phe thr arg lys leu cys ser leu asp asn gly asp 135
TGT GAC CAG TTC TGC CAC GAG GAA CAG AAC TCT GTG GTG TGC TCC
cys asp gln phe cys his glu glu gln asn ser val val cys ser 150
TGC GCC CGC GGG TAC ACC CTG GCT GAC AAC GGC AAG GCC TGC ATT
cys ala arg gly tyr thr leu ala asp asn gly lys ala cys ile 165
CCC ACA GGG CCC TAC CCC TGT GGG AAA CAG ACC CTG GAA CGC AGG
pro thr gly pro tyr pro cys gly lys gln thr leu glu arg arg 180
AAG AGG TCA GTG GCC CAG GCC ACC AGC AGC AGC GGG GAG GCC CCT
lys arg ser val ala gln ala thr ser ser ser gly glu ala pro 195
GAC AGC ATC ACA TGG AAG CCA TAT GAT GCA GCC GAC CTG GAC CCC
asp ser ile thr trp lys pro tyr asp ala ala asp leu asp pro 210
ACC GAG AAC CCC TTC GAC CTG CTT GAC TTC AAC CAG ACG CAG CCT
thr glu asn pro phe asp leu leu asp phe asn gln thr gln pro 225
GAG AGG GGC GAC AAC AAC CTC ACC AGG ATC GTG GGA GGC CAG GAA
glu arg gly asp asn asn leu thr arg ile val gly gly gln glu 240
TGC AAG GAC GGG GAG TGT CCC TGG CAG GCC CTG CTC ATC AAT GAG
cys lys asp gly glu cys pro trp gln ala leu leu ile asn glu 255
GAA AAC GAG GGT TTC TGT GGT GGA ACC ATT CTG AGC GAG TTC TAC
glu asn glu gly phe cys gly gly thr ile leu ser glu phe tyr 270
ATC CTA ACG GCA GCC CAC TGT CTC TAC CAA GCC AAG AGA TTC AAG
ile leu thr ala ala his cys leu tyr gln ala lys arg phe lys 285
GTG AGG GTA GGG GAC CGG AAC ACG GAG CAG GAG GAG GGC GGT GAG
val arg val gly asp arg asn thr glu gln glu glu gly gly glu 300
GCG GTG CAC GAG GTG GAG GTG GTC ATC AAG CAC AAC CGG TTC ACA
ala val his glu val glu val val ile lys his asn arg phe thr 315
AAG GAG ACC TAT GAC TTC GAC ATC GCC GTG CTC CGG CTC AAG ACC
lys glu thr tyr asp phe asp ile ala val leu arg leu lys thr 330
CCC ATC ACC TTC CGC ATG AAC GTG GCG CCT GCC TGC CTC CCC GAG
pro ile thr phe arg met asn val ala pro ala cys leu pro glu 345
CGT GAC TGG GCC GAG TCC ACG CTG ATG ACG CAG AAG ACG GGG ATT
arg asp trp ala glu ser thr leu met thr gln lys thr gly ile 360
GTG AGC GGC TTC GGG CGC ACC CAC GAG AAG GGC CGG CAG TCC ACC
val ser gly phe gly arg thr his glu lys gly arg gln ser thr 375
AGG CTC AAG ATG CTG GAG GTG CCC TAC GTG GAC CGC AAC AGC TGC
arg leu lys met leu glu val pro tyr val asp arg asn ser cys 390
AAG CTG TCC AGC AGC TTC ATC ATC ACC CAG AAC ATG TTC TGT GCC
lys leu ser ser ser phe ile ile thr gln asn met phe cys ala 405
GGC TAC GAC ACC AAG CAG GAG GAT GCC TGC CAG GGG GAC AGC GGG
gly tyr asp thr lys gln glu asp ala cys gln gly asp ser gly 420
GGC CCG CAC GTC ACC CGC TTC AAG GAC ACC TAC TTC GTG ACA GGC
gly pro his val thr arg phe lys asp thr tyr phe val thr gly 435
ATC GTC AGC TGG GGA GAG GGC TGT GCC CGT AAG GGG AAG TAC GGG
ile val ser trp gly glu gly cys ala arg lys gly lys tyr gly 450
ATC TAC ACC AAG GTC ACC GCC TTC CTC AAG TGG ATC GAC AGG TCC
ile tyr thr lys val thr ala phe leu lys trp ile asp arg ser 465
ATG AAA ACC AGG GGC TTG CCC AAG GCC AAG AGC CAT GCC CCG GAG
met lys thr arg gly leu pro lys ala lys ser his ala pro glu 480
GTC ATA ACG TCC TCT CCA TTA AAG TGA
val ile thr ser ser pro leu lys ter
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