Рис. F 7 seq
Нуклеотидная и аминокислотная последовательности
гена фактора коагуляции VII (F VII) человека.
ATG GTC TCC CAG GCC CTC AGG CTC CTC TGC CTT CTG CTT GGG CTT
met val ser gln ala leu arg leu leu cys leu leu leu gly leu 15
CAG GGC TGC CTG GCT GCA GGC GGG GTC GCT AAG GCC TCA GGA GGA
gln gly cys leu ala ala gly gly val ala lys ala ser gly gly 30
GAA ACA CGG GAC ATG CCG TGG AAG CCG GGG CCT CAC AGA GTC TTC
glu thr arg asp met pro trp lys pro gly pro his arg val phe 45
GTA ACC CAG GAG GAA GCC CAC GGC GTC CTG CAC CGG CGC CGG CGC
val thr gln glu glu ala his gly val leu his arg arg arg arg 60
GCC AAC GCG TTC CTG GAG GAG CTG CGG CCG GGC TCC CTG GAG AGG
ala asn ala phe leu glu glu leu arg pro gly ser leu glu arg 75
GAG TGC AAG GAG GAG CAG TGC TCC TTC GAG GAG GCC CGG GAG ATC
glu cys lys glu glu gln cys ser phe glu glu ala arg glu ile 90
TTC AAG GAC GCG GAG AGG ACG AAG CTG TTC TGG ATT TCT TAC AGT
phe lys asp ala glu arg thr lys leu phe trp ile ser tyr ser 105
GAT GGG GAC CAG TGT GCC TCA AGT CCA TGC CAG AAT GGG GGC TCC
asp gly asp gln cys ala ser ser pro cys gln asn gly gly ser 120
TGC AAG GAC CAG CTC CAG TCC TAT ATC TGC TTC TGC CTC CCT GCC
cys lys asp gln leu gln ser tyr ile cys phe cys leu pro ala 135
TTC GAG GGC CGG AAC TGT GAG ACG CAC AAG GAT GAC CAG CTG ATC
phe glu gly arg asn cys glu thr his lys asp asp gln leu ile 150
TGT GTG AAC GAG AAC GGC GGC TGT GAG CAG TAC TGC AGT GAC CAC
cys val asn glu asn gly gly cys glu gln tyr cys ser asp his 165
ACG GGC ACC AAG CGC TCC TGT CGG TGC CAC GAG GGG TAC TCT CTG
thr gly thr lys arg ser cys arg cys his glu gly tyr ser leu 180
CTG GCA GAC GGG GTG TCC TGC ACA CCC ACA GTT GAA TAT CCA TGT
leu ala asp gly val ser cys thr pro thr val glu tyr pro cys 195
GGA AAA ATA CCT ATT CTA GAA AAA AGA AAT GCC AGC AAA CCC CAA
gly lys ile pro ile leu glu lys arg asn ala ser lys pro gln 210
GGC CGA ATT GTG GGG GGC AAG GTG TGC CCC AAA GGG GAG TGT CCA
gly arg ile val gly gly lys val cys pro lys gly glu cys pro 225
TGG CAG GTC CTG TTG TTG GTG AAT GGA GCT CAG TTG TGT GGG GGG
trp gln val leu leu leu val asn gly ala gln leu cys gly gly 240
ACC CTG ATC AAC ACC ATC TGG GTG GTC TCC GCG GCC CAC TGT TTC
thr leu ile asn thr ile trp val val ser ala ala his cys phe 255
GAC AAA ATC AAG AAC TGG AGG AAC CTG ATC GCG GTG CTG GGC GAG
asp lys ile lys asn trp arg asn leu ile ala val leu gly glu 270
CAC GAC CTC AGC GAG CAC GAC GGG GAT GAG CAG AGC CGG CGG GTG
his asp leu ser glu his asp gly asp glu gln ser arg arg val 285
GCG CAG GTC ATC ATC CCC AGC ACG TAC GTC CCG GGC ACC ACC AAC
ala gln val ile ile pro ser thr tyr val pro gly thr thr asn 300
CAC GAC ATC GCG CTG CTC CGC CTG CAC CAG CCC GTG GTC CTC ACT
his asp ile ala leu leu arg leu his gln pro val val leu thr 315
GAC CAT GTG GTG CCC CTC TGC CTG CCC GAA CGG ACG TTC TCT GAG
asp his val val pro leu cys leu pro glu arg thr phe ser glu 330
AGG ACG CTG GCC TTC GTG CGC TTC TCA TTG GTC AGC GGC TGG GGC
arg thr leu ala phe val arg phe ser leu val ser gly trp gly 345
CAG CTG CTG GAC CGT GGC GCC ACG GCC CTG GAG CTC ATG GTG CTC
gln leu leu asp arg gly ala thr ala leu glu leu met val leu 360
AAC GTG CCC CGG CTG ATG ACC CAG GAC TGC CTG CAG CAG TCA CGG
asn val pro arg leu met thr gln asp cys leu gln gln ser arg 375
AAG GTG GGA GAC TCC CCA AAT ATC ACG GAG TAC ATG TTC TGT GCC
lys val gly asp ser pro asn ile thr glu tyr met phe cys ala 390
GGC TAC TCG GAT GGC AGC AAG GAC TCC TGC AAG GGG GAC AGT GGA
gly tyr ser asp gly ser lys asp ser cys lys gly asp ser gly 405
GGC CCA CAT GCC ACC CAC TAC CGG GGC ACG TGG TAC CTG ACG GGC
gly pro his ala thr his tyr arg gly thr trp tyr leu thr gly 420
ATC GTC AGC TGG GGC CAG GGC TGC GCA ACC GTG GGC CAC TTT GGG
ile val ser trp gly gln gly cys ala thr val gly his phe gly 435
GTG TAC ACC AGG GTC TCC CAG TAC ATC GAG TGG CTG CAA AAG CTC
val tyr thr arg val ser gln tyr ile glu trp leu gln lys leu 450
ATG CGC TCA GAG CCA CGC CCA GGA GTC CTC CTG CGA GCC CCA TTT
met arg ser glu pro arg pro gly val leu leu arg ala pro phe 465
CCC TAG
pro ter
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