Рис. AGA seq.
Нуклеотидная и аминокислотная последовательности аспартилгликозаминидазы aspartylglucosaminidase (AGA) человека. ATG GCG CGG AAG TCG AAC TTG CCT GTG CTT CTC GTG CCG TTT CTG met ala arg lys ser asn leu pro val leu leu val pro phe leu 15 CTC TGC CAG GCC CTA GTG CGC TGC TCC AGC CCT CTG CCC CTG GTC leu cys gln ala leu val arg cys ser ser pro leu pro leu val 30 GTC AAC ACT TGG CCC TTT AAG AAT GCA ACC GAA GCA GCG TGG AGG val asn thr trp pro phe lys asn ala thr glu ala ala trp arg 45 GCA TTA GCA TCT GGA GGC TCT GCC CTG GAT GCA GTG GAG AGC GGC ala leu ala ser gly gly ser ala leu asp ala val glu ser gly 60 TGT GCC ATG TGT GAG AGA GAG CAG TGT GAC GGC TCT GTA GGC TTT cys ala met cys glu arg glu gln cys asp gly ser val gly phe 75 GGA GGA AGT CCT GAT GAA CTT GGA GAA ACC ACA CTA GAT GCC ATG gly gly ser pro asp glu leu gly glu thr thr leu asp ala met 90 ATC ATG GAT GGC ACT ACT ATG GAT GTA GGA GCA GTA GGA GAT CTC ile met asp gly thr thr met asp val gly ala val gly asp leu 105 AGA CGA ATT AAA AAT GCT ATT GGT GTG GCA CGG AAA GTA CTG GAA arg arg ile lys asn ala ile gly val ala arg lys val leu glu 120 CAT ACA ACA CAC ACA CTT TTA GTA GGA GAG TCA GCC ACC ACA TTT his thr thr his thr leu leu val gly glu ser ala thr thr phe 135 GCT CAA AGT ATG GGG TTT ATC AAT GAA GAC TTA TCT ACC AGT GCT ala gln ser met gly phe ile asn glu asp leu ser thr ser ala 150 TCT CAA GCT CTT CAT TCA GAT TGG CTT GCT CGG AAT TGC CAG CCA ser gln ala leu his ser asp trp leu ala arg asn cys gln pro 165 AAT TAT TGG AGG AAT GTT ATA CCA GAT CCC TCA AAA TAC TGC GGA asn tyr trp arg asn val ile pro asp pro ser lys tyr cys gly 180 CCC TAC AAA CCA CCT GGT ATC TTA AAG CAG GAT ATT CCT ATC CAT pro tyr lys pro pro gly ile leu lys gln asp ile pro ile his 195 AAA GAA ACA GAA GAT GAT CGT GGT CAT GAC ACT ATT GGC ATG GTT lys glu thr glu asp asp arg gly his asp thr ile gly met val 210 GTA ATC CAT AAG ACA GGA CAT ATT GCT GCT GGT ACA TCT ACA AAT val ile his lys thr gly his ile ala ala gly thr ser thr asn 225 GGT ATA AAA TTC AAA ATA CAT GGC CGT GTA GGA GAC TCA CCA ATA gly ile lys phe lys ile his gly arg val gly asp ser pro ile 240 CCT GGA GCT GGA GCC TAT GCT GAC GAT ACT GCA GGG GCA GCC GCA pro gly ala gly ala tyr ala asp asp thr ala gly ala ala ala 255 GCC ACT GGG AAT GGT GAT ATA TTG ATG CGC TTC CTG CCA AGC TAC ala thr gly asn gly asp ile leu met arg phe leu pro ser tyr 270 CAA GCT GTA GAA TAC ATG AGA AGA GGA GAA GAT CCA ACC ATA GCT gln ala val glu tyr met arg arg gly glu asp pro thr ile ala 285 TGC CAA AAA GTG ATT TCA AGA ATC CAG AAG CAT TTT CCA GAA TTC cys gln lys val ile ser arg ile gln lys his phe pro glu phe 300 TTT GGG GCT GTT ATA TGT GCC AAT GTG ACT GGA AGT TAC GGT GCT phe gly ala val ile cys ala asn val thr gly ser tyr gly ala 315 GCT TGC AAT AAA CTT TCA ACA TTT ACT CAG TTT AGT TTC ATG GTT ala cys asn lys leu ser thr phe thr gln phe ser phe met val 330 TAT AAT TCC GAA AAA AAT CAG CCA ACT GAG GAA AAA GTG GAC TGC tyr asn ser glu lys asn gln pro thr glu glu lys val asp cys 345 ATC TAA ile ter
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