Gene: [00.0/KPNA1] karyopherin (importin) alpha 1 (SRP1-beta); RAG (recombination activating gene) cohort 2; suppressor of RNA polymerase I mutation (Saccharomyces) homolog; [RCH2 SRP1 ]

FUN	Karyopherins, or importins, are cytoplasmic proteins that recognize nuclear localization signals (NLSs) on the amino acid sequences of karyophilic proteins and dock NLS-containing proteins to the nuclear pore complex (nuclear import)."
FAG	The following genes coding for alpha karyopherins have been found: GEM:00.0/KPNA1; GEM:17q23/KPNA2; GEM:13q143/KPNA3; GEM:00.0/KPNA4; GEM:00.0/KPNA6. See also GEM:00.0/KPNB1; GEM:00.0/KPNB2; GEM:00.0/KPNB3. [2] About recombination activating genes see GEM:11p13/RAG1 and GEM:11p13/RAG2."
REF	CLO,SEQ "Cortes P &: PNAS, 91, 7633-7637, 1994 CLO,SEQ "O'Neill RE, Palese P: Virology, 206,116-125, 1995
SWI	SWISSPROT: P52294
KEY	sign, trp
CLA	coding, basic
LOC	RS
MIM	MIM: 600686
SYN	RCH2 SRP1