Gene: [01q211/NPR1] natriuretic peptide receptor A (guanylate cyclase A); guanylate cyclase A (atrionatriuretic peptide receptor A);
|
COM |
Lowe-1990 assigned the NPR1 gene to Chr 1q21-22. Gelb-1997 refined the location to Chr 1q21.1." |
|
FUN |
[1] Systematic name: GTP pyrophosphate-lyase (cyclizing).
[2] Reaction catalyzed: GTP = 3',5'-cyclic GMP + pyrophosphate. Also acts on ITP and dGTP." |
|
REL |
GEM:09p/NPR2; GEM:05p1/NPR3. See also GEM:01p362/NPPA; GEM:01p362/NPPB; GEM:02q/NPPC." |
|
REF |
CLO,SEQ,COD,MOP "Chinkers M &: Nature, 338, 78-83, 1989 FUN,EXP,MEB "Garbers DL: JBC, 264, 9103-9106, 1989 LOC "Gelb BD &: Genomics, 39, N3, 409-411, 1997 PEP,FUN "Hardman JG, Sutherland EW: JBC, 244, 6363-6370, 1969 FUN,EXP,MEB "Inagami T: JBC, 264, 3043-3046, 1989 FUN,EXP,MEB "Leitman DC &: JBC, 261, 11650-11655, 1986 LOC,FAG "Lowe DG &: Genomics, 8, N2, 304-312, 1990 CLO,SEQ,COD,MOP "Lowe DG &: EMBO J, 8, 1377-1384, 1989 FUN,EXP,MEB "Schulz S &: Cell, 58, 1155-1162, 1989 EVO,SEQ "Singh S &: Nature, 334, 708-712, 1988 EVO,SEQ "Thorpe DS, Garbers DL: JBC, 246, 6545-6549, 1989 |
|
KEY |
horm, neu, card, mem, recp, nucm |
|
CLA |
coding, basic |
|
LOC |
01 q21.1 |
|
MIM |
MIM: 108960 |
|
EZN |
ENZYME: 4.6.1.2 |
