Gene: [01q3/F13B] coagulation factor XIII, B polypeptide; fibrin stabilizing factor, B subunit; glutaminyl-peptide gamma-glutamyltransferase, B subunit;


FUN

[1] Contrary to the alpha peptide (GEM:06p2/F13A1), the beta subunit of the factor XIII does not exhibit a catalytic activity and seems to perform the transport and defence (from serum proteases) functions with respect to F13A1.
[2] Systematic name: glutaminyl peptide:amine gamma-glutamyl transferase.
[3]-The reaction catalyzed: protein glutamine + alkylamine = protein N5-alkylglutamine + NH(3)."

ASS

The association between schizophrenia and F13B has been described (Nakamura-1990)."

REF

PAT,FOG "Barbui &: Brit J Haematol, 38, 267-271, 1978
LOC,LIN "Bender K &: Genet Epidemiol, 4, 43-49, 1987
POL,FOG,POG "Board PG: Ann Hum Genet, 48, 223-228, 1984
POL,FOG,POG "Board PG: AJHG, 32, 348-353, 1980
PRO,GEN,SEQ "Bottenus RE &: Biochemistry, 29, N51, 11195-11209, 1990
LOC,LIN "De Cordoba &: Immunogenetics, 28, 452-458, 1988
LOC,LIN "Eiberg H &: CCG, 46, (HGM9), 610, 1987
LOC,LIN "Eiberg H &: Clin Genet, 27, 206, 1985
LOC,LIN "Eiberg H &: CCG, 37, (HGM7), 463, 1984
PAT,FOG "Girolami &: Folia Haematol, 15, 131-141, 1978
PRO,SEQ,EXP,MOP "Ichinose A &: Biochemistry, 25, 4633-4638, 1986
POL,FOG,POG "Kamboh MI, Ferrel: AJHG, 39, 817-825, 1986
POL,FOG,POG "Kera Y &: Hum Genet, 59, 360-364, 1981
LOC,LIN "Leppert &: CCG, 46, (HGM9), 647, 1987
ASS "Nakamura &: Brain Dysfunct, 3, 175-182, 1990
POL,FOG,POG "Nakamura &: Ann Hum Genet, 46, 203-207, 1982
POL,FOG,POG "Nishigaki &: Jpn J Hum Genet, 27, 265-270, 1982
LOC,LIN,MAP "O'Connell P &: Genomics, 4, 12-20, 1989
LOC,LIN "Rocha &: CCG, 51, (HGM10), 1067, 1989
LOC,MOL,POL "Webb GC &: Hum Genet, 81, 157-160, 1989

SWI

SWISSPROT: P05160

KEY

pep, hem, trp, clot

CLA

coding, basic

LOC

01 q31-32.1

MIM

MIM: 134580

EZN

ENZYME: 2.3.2.13

鸯铗痂蝈 蜞赕:

  • Gene: [00.0/SCZD1] schizophrenia disorder 1;
  • 暑嚆箅鲨铐睇 羿牝铕 XIII. 羊痤屙桢 沐磬 "" 耋狷邃桧桷 羿牝铕 XIII
  • Gene: [01q3/RP12] retinitis pigmentosa 12 (autosomal recessive);
  • 暑嚆箅鲨铐睇 羿牝铕 XIII. 祟赅腓玎鲨 沐磬