Gene: [02p23/SRD5A2] steroid-5-alpha-reductase, alpha polypeptide 2; pseudohermaphroditism, male (steroid-5-alpha-reductase alpha 2 deficiency); pseudovaginal perineoscrotal hypospadias;


FUN

Systematic name: 3-oxo-5-alpha-steroid:(acceptor) delta(4)-oxidoreductase. The reaction catalyzed: a 3-oxo-5-alpha-steroid + acceptor = = a 3-oxo-delta(4)-steroid + reduced acceptor."

FAG

See GEM:05p15/SRD5A1.

REF

PRO,LOC,LIN,POL "Morissette J &: CCG, 73, 304-307, 1996
CLO,SEQ,MUT "Thigpen AE &: J Clin Invest, 90, 799-809, 1992

SWI

SWISSPROT: P31213

KEY

horm, ster, sex

CLA

coding, basic

LOC

02 p23

MIM

MIM: 264600

EZN

ENZYME: 1.3.99.5

Смотрите также:

  • ген 5альфа-редуктазы
  • 5альфа-редуктаза II типа