Gene: [05p15/SRD5A1] steroid-5-alpha-reductase, alpha polypeptide 1; pseudohermaphroditism, male (steroid-5-alpha-reductase alpha 1 deficiency);


FUN

Systematic name: 3-oxo-5-alpha-steroid:(acceptor) delta(4)-oxidoreductase. The reaction catalyzed: a 3-oxo-5-alpha-steroid + acceptor = = a 3-oxo-delta(4)-steroid + reduced acceptor."

FAG

Two loci coding for steroid-5-alpha-reductase alpha polypeptide and a SRD5A pseudogene have been identified in the human genome: GEM:05p15/SRD5A1; GEM:02p23/SRD5A2; GEM:0Xq2/SRD5AP1."

REF

LOC,EAG,HUM,MOU "Hsieh &: CCG, 58, (HGM11), 1897, 1991

SWI

SWISSPROT: P18405

KEY

horm, lip, sex

CLA

coding, basic

LOC

05 p15

MIM

MIM: 184753

EZN

ENZYME: 1.3.99.5