Gene: [02q35/XRCC5] X-ray repair complementing defective repair in Chinese hamster cells 5; thyroid autoantigen, 80kD (antigen Ku; p80; lupus antigen); ATP-dependent DNA helicase II, 86kD;
FAG | [1] An
ATP-dependent DNA unwinding enzyme helicase II is a heterodimer of 70kD
(GEM:22q13/TAKU) and 86kD subunits
(Tuteja-1994). [2] Ku autoantigen consists of 2 proteins of molecular mass of 70kD (GEM:22q13/TAKU) and 80kD. The p70/p80 complex binds to the folk-like ends of double-stranded DNA in a cell cycle-dependent manner." |
REF | CLO,LOC "Blunt T &:
Genomics, 30, 320-328, 1995 CLO,SEQ,FUN "Cai QQ &: CCG, 65, 221-227, 1994 LOC "Chen DJ &: Genomics, 21, 423-427, 1994 LOC "Chen DJ &: Genomics, 13, 1088-1092, 1992 CLO,SEQ,FUN "Genersch E &: EMBO J, 14, N4, 791-800, 1995 LOC "Jeggo PA &: PNAS, 89, 6423-6427, 1992 CLO,SEQ,FUN "Roberts MR &: PNAS, 91, 6354-6358, 1994 CLO,SEQ,FUN "Taccioli GE &: Science, 265, 1442-1445, 1994 CLO,SEQ,FUN "Tuteja N &: EMBO J, 13, 4991-5001, 1994 |
SWI | SWISSPROT: P13010 |
KEY | repr |
CLA | coding, basic |
LOC | 02 q35 |
MIM | MIM: 194364 |
EZN | ? |
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