Gene: [03p24/RARB] retinoic acid receptor, beta; HBV-activated protein; [HAP ]


FAG

[1] Genes for retinol-binding proteins are located in other regions of chromosome 3 (GEM:03q2/RBPC1, GEM:03q2/RBPC2).
[2] About other genes for the retinoic acid receptor, see GEM:17q112/RARA."

HIS

This gene was identified as an integration site for the hepatitis B virus in hepatocellular carcinoma (Dejean-1986), and its product was named HAP (hepatitis B virus-activated protein). However, HAP was thereafter shown to be identical to the beta receptor for retinoic acid."

POL

Probe pCOD20 is a 1.4 kb DNA fragment that has been cloned at SmaI site in plasmide pTZ18U. ------------------ RFLP-system: ------------------
[1] MspI A-RFLP (Datson-1989; Probe [1]): alleles A1= 8.1 kb/(popul.freq. 0.88); A2= 7.7/(0.12)"

REF

PRO,SEQ,EVO,EXP,FUN "Brand N &: Nature, 332, N6167, 850-853, 1988
PRO,POL "Datson NA &: NAR, 17, 8897, 1989
TRC,SEQ,EXP,FUN "de The H &: Nature, 343, 177-180, 1990
EVO,EXP,FUN "de The H &: Nature, 330, 667-670, 1987
HIS,LOC,SEQ,EVO,EXP "Dejean A &: Nature, 322, 70-72, 1986
LOC "Mattei MG &: Hum Genet, 80, 189-190, 1988
FUN,PEP,EXP "Robertson M: Nature, 330, 420-421, 1987

KEY

recp, vir, vit

CLA

coding, basic

LOC

03 p24.3-.2

MIM

MIM: 180220

SYN

HAP