Gene: [05q13/PIK3R1] phosphatidylinositol 3-kinase, regulatory, polypeptide 1 (p85 alpha); [p85a ]
MOP | [1]
Phosphatidylinositol 3-kinase is a heterodimer of catalytic (p110) (see
GEM:03q263/PIK3CA) and regulatory (p85)
subunits. [2] The p85 subunit lacks PI3-kinase activity and acts as an adaptor, coupling the p110 subunit to activated protein tyrosine kinases." |
REL | GEM:19q13/PIK3R2. |
REF | LOC "Cannizzaro LA &: Cancer Res, 51, 3818-3820, 1991 CLO,SEQ "Escobedo JA &: Cell, 65, 75-82, 1991 LOC "Huschenbett J &: Hum Genet, 94, 427-431, 1994 CLO,SEQ "Koyama S &: Cell, 72, 945-952, 1993 CLO,SEQ "Otsu M &: Cell, 65, 91-104, 1991 CLO,SEQ "Skolnik EY &: Cell, 65, 83-90, 1991 CLO,SEQ "Volinia S &: Oncogene, 7, 789-793, 1992 |
SWI | SWISSPROT: P27986 |
KEY | lip, neu |
CLA | coding, basic |
LOC | 05 q13 |
MIM | MIM: 171833 |
SYN | p85a |
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