Gene: [03q263/PIK3CA] phosphatidylinositol 3-kinase, catalytic, alpha polypeptide;


MOP

Phosphatidylinositol 3-kinase is a heterodimer of catalytic (p110) and regulatory (p85) subunits (see GEM:05q13/PIK3R1)."

FAG

[1] Three other genes for PIK3 catalytic isoforms were cloned (beta GEM:00.0/PIK3CB, gamma GEM:00.0/PIK3CG, and delta GEM:00.0/PIK3CD).
[2] On phosphatidylinositol-4 kinases see GEM:00.0/PIK4CA and GEM:01q21/PIK4CB."

REF

COD,SEQ "Hiles ID &: Cell, 70, 419-429, 1992
COD,SEQ,LOC "Volinia S &: Genomics, 24, 472-477, 1994

KEY

lip, neu

CLA

coding, basic

LOC

03 q26.3

MIM

MIM: 171834

EZN

ENZYME: 2.7.1.137

Смотрите также:

  • PI3K: роль в трансформации клеток
  • HUGEN-3-киназа инозитолтрифосфата
  • HUGEN-Киназа: 3-Киназа