Gene: [05q31/IL5] interleukin 5 (colony-stimulating factor, eosinophil); eosinophil differentiation factor (T-cell replacing factor); [CSFE EDF TRF ]


COM

The GDB indicates the IL5 location less precisely: 05q23-31.

LIN

See GEM:05q31/IL4.

GEN

The gene length is 2.2 kb. Exons: 4; introns: 3.

MOP

The polypeptide product comprises 134 amino acid residues.

PRO

Probe pEDFH-1 contains a 3.2-kb BamHI gDNA fragment (covering completely the gene IL5). It is cloned at SmaI site and expressed in eukaryotic cells in the vector pCEXV-3 (Miller &: J Immunol, 134, 4212, 1985)."

FAG

The gene for interleukin 5 alpha receptor has been mapped: GEM:03p2/IL5RA."

REL

See GEM:02q13/IL1A.

REF

GEN,SEQ,PRO,EXP "Campbell HD &: PNAS, 84, N19, 6629-6633, 1987
LOC,PRO,FAG "Le Beau MM &: Blood, 73, N3, 647-650, 1989
LOC,PRO,FAG "Sutherland GR &: Blood, 71, N4, 1150-1152, 1988
LOC,PRO,FAG "Takahashi M &: Genomics, 4, 47-52, 1989
GEN,FAG,MAF "van Leeuwen BH &: Blood, 73, N5, 1142-1148, 1989
GEN,FAG,MAF "see also GEM:05q31/IL4

SWI

SWISSPROT: P05113

KEY

imm, onc, cyk

CLA

coding, basic

LOC

05 q31

MIM

MIM: 147850

SYN

CSFE EDF TRF

Смотрите также:

  • ИЛ-5 (Интерлейкин-5, ИЛ-5)