Gene: [05q3/ITK] protein tyrosine kinase ITK, non-receptor (T-cell-specific); T-cell-specific tyrosine kinase; homolog of mouse itk/tsk;


COM

The ITK gene location was refined as 05 q34 by FISH (Tate-1996).

FAG

The ITK gene initially identified as a homolog of mouse T-cell itk/tsk tyrosine kinase belongs to a subfamily of nonreceptor tyrosine kinases, which includes following genes: GEM:0Xq2/BTK; GEM:05q3/ITK; GEM:04p12/TEC; GEM:04p12/TXK."

REF

CLO,SEQ,STR,LOC "Gibson S &: Blood, 82, 1561-1572, 1993
LOC "Janis EM &: Genomics, 23, 269-271, 1994
PRO,LOC,EAG,HUM,MOU "Tate G &: CCG, 74, 96-98, 1996

SWI

SWISSPROT: Q08881

KEY

imm, pep

CLA

coding, basic

LOC

05 q31-32 ? q34

MIM

MIM: 186973

EZN

ENZYME: 2.7.1.112

Смотрите также:

  • Gene: [0Xp222/BMX] protein tyrosine kinase BMX, non-receptor; bone marrow kinase, X-linked;
  • Itk (Tsk)