Gene: [06p213/TAP1] transporter 1, ABC (ATP binding cassette); traffic ATPase TAP1 (subunit ?);
|
FAG |
See GEM:09q/ABC1. |
|
FUN |
Newly assembled major histocompatibility complex (MHC) class I molecules (see FAM:MHC1/06p2133), together with the endoplasmic reticulum chaperone calreticulin (GEM:19p132/CALR), interact with the transporter associated with antigen processing (this locus) through a molecule called tapasin (GEM:06p213/TAPBP; Sadasivan-1996)." |
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REF |
PRO,FAG,REL "Bahram S &: PNAS, 88, 10094-10098, 1991 PRO,FAG,REL "Bodmer JG &: Tissue Antigens, 39, 161-173, 1992 PRO,FAG,REL "Cerundolo V &: Nature, 345, 449-452, 1990 PRO,FAG,REL "Hanson IM &: Genomics, 10, 417-424, 1991 POL,FAG "Moins-Teisserenc H &: Immunogenetics, 40, N3, 242, 1994 EXP,FUN "Sadasivan B &: Immunity, 5, 103-114, 1996 PRO,FAG,REL "Spies T &: Nature, 351, 323-324, 1991 LOC,FAG "Spies T &: Nature, 348, N6303, 744-747, 1990 POL,FAG "Szafer F &: Immunogenetics, 39, 374, 1994 LOC,FAG "Trowsdale J &: Nature, 348, N6303, 741-744, 1990 |
|
KEY |
nucm, trp |
|
CLA |
coding, basic |
|
LOC |
06 p21.3 |
|
MIM |
MIM: 170260 |
|
EZN |
ENZYME: 3.6.1.? |
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