Gene: [09q/ABC1] ATP-binding cassette 1; traffic ATPase ABC1 (subunit ?);
|
FAG |
[1] The family of ATP-binding cassette (ABC) transporters (ABC1;
GEM:09q34/ABC2; GEM:16p133/ABC3; GEM:0Xq1/ABC7; GEM:06p213/TAP1;
GEM:06p213/TAP2) includes traffic ATPases
encoded as a single
multifunctional protein.
[2] On retina-specific ABC transporter see GEM:01p13/ABCR." |
|
MOP |
The ABC1 protein (so as ABC2) is a large, internally symmetrical molecule that contains complete information for a functional 'channel-like' structure, a feature typical of the mammalian transporters at the plasma membrane. The 2 halves of the molecule does not share extensive sequence similarity, apart from the nucleotide binding domains." |
|
REF |
REV "Allikmets R &: Hum Mol Genet, 5, 1649-1655, 1996 PRO,LOC,FAG "Luciani MF &: Genomics, 21, 150-159, 1994 |
|
KEY |
nucm, trp |
|
CLA |
coding, basic |
|
LOC |
09 q22-31 |
|
MIM |
MIM: 600046 |
|
EZN |
ENZYME: 3.6.1.? |
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