Gene: [06p25/PI9] protease inhibitor 9 (ovalbumin type); cytoplasmic antiproteinase 3 (CAP3); [CAP3 ]
|
COM |
The PI9 gene is mapped to Chr 6p25 using FISH (Eyre-1996). |
|
FAG |
There is a cluster of serpins at Chr 6p which includes PI6 (GEM:06p2/PI6) and ELANH2 (GEM:06p2/ELANH2)." |
|
FUN |
PI9 forms an SDS-resistant complex with granzyme B (GEM:14q112/CTLA1), suggesting that these 2 proteins may form a physiologically significant serpin-serine proteinase interaction. PI9 is expressed in immune tissue and may be involved in immune response (Sun-1996). On other serpin functions see in GEM:14q321/PI1[:FAG]." |
|
REF |
LOC "Eyre HJ &: Genomics, 37, 406-408, 1996 COD,EXP,SEQ,FAG "Sprecher CA &: JBC, 270, 29854-29861, 1995 CLO,SEQ,EVO,EXP,FUN,MEB "Sun J &: JBC, 271, 27802-27809, 1996 |
|
KEY |
serp |
|
CLA |
coding, basic |
|
LOC |
06 p25 |
|
MIM |
MIM: 601799 |
|
SYN |
CAP3 |
