Gene: [06q12/ME1] malic enzyme 1, soluble;
FUN | Systematic name: L-malate:NADP+ oxidoreductase (decarboxylizing oxaloacetate). Catalyzes the oxidative decarboxylation of malate: L-malate + NADP+ = pyruvate + carbon dioxide + NADPH. The enzyme provides the relation between glycolysis and the citric acid cycle." |
FAG | A gene for the mitochondrial isoform of this enzyme is mapped on the short arm of this chromosome (GEM:06p2/ME2). Genes for NAD-malate dehydrogenases (GEM:02p23/MDH1 and GEM:07q/MDH2) are located in chromosomes 2 and 7. On the biochemical classification of malate dehydrogenases, see GEM:02p23/MDH1." |
REF | LOC "Chen &: AJHG, 25,
200-207, 1973 LOC "Meera Khan &: CCG, 37, (HGM7), 537, 1984 |
SWI | SWISSPROT: P48163 |
KEY | cytr |
CLA | coding, basic |
LOC | 06 q12 |
MIM | MIM: 154250 |
EZN | ENZYME: 1.1.1.40 |
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