Gene: [02p23/MDH1] malate dehydrogenase, NAD (soluble);
FUN | [1]
Systematic name: (S)-malate:NAD+ oxidoreductase. The reaction catalyzed:
(S)-malate + NAD+ = oxaloacetate + NADH. [2] EN-IUB indicates, under the common name 'malate dehydrogenase', four enzymes that differ in pattern of malate oxidation (with or without decarboxylation), range of substrate specificity, and the nature of the proton acceptor used (NAD+ or NADP+); see EC:1.1.1.37, EC:1.1.1.38, EC:1.1.1.39, and EC:1.1.1.40." |
REL | GEM:02p23/MDH1; GEM:06p2/ME2; GEM:06q12/ME1; GEM:07q/MDH2. |
REF | PEP,SEQ "Birktoft &:
PNAS, 79, 6166-6170, 1982 LOC,LIN "Creagan &: AJHG, 26, 604-613, 1974 LOC,LIN "Gee PA &: CCG, 13, 89-90, 1974 LOC,LIN "Hamerton JL &: AJHG, 27, 595-608, 1975 LOC,LIN "Larson LM &: Clin Genet, 22, 220-225, 1982 FOG "Leakey &: Hum Hered, 22, 542-551, 1972 LOC,LIN "Shows TB: Biochem Genet, 7, 193-204, 1972 |
SWI | SWISSPROT: P40925 |
KEY | cytr |
CLA | coding, basic |
LOC | 02 p23 |
MIM | MIM: 154200 |
EZN | ENZYME: 1.1.1.37 |
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