Gene: [07p1/IGFB1] insulin-like growth factor binding protein 1 (25-35kD); placental protein 12 (IGF-binding protein); [IGFBP1 IBP1 ]
GEN | The gene length is 5.9 kb. Exons: 4. |
MOP | Insulin-like growth factors (IGF; see GEM:12q23/IGF1) are circulating in serum, being tightly bound with specific IGF-binding proteins, which are present in human as two major forms, low-molecular one (25-35 kD) and high-molecular one (150 kD)." |
FAG | The following IGFB genes are identified in the human genome: GEM:07p1/IGFB1; GEM:02q3/IGFB2; GEM:07p1/IGFB3; GEM:17q/IGFB4; GEM:00.0/IGFB5; GEM:12^/IGFB6; GEM:04q12/IGFB7; GEM:01p/IGFB10. See also GEM:06^/IGFALS." |
REF | LOC,FAG,EVO,POL
"Alitalo &: CCG, 51, (HGM10), 950, 1989a LOC,FAG,EVO,POL "Alitalo &: Hum Genet, 83, 335-338, 1989b REV,NOM "Ballard &: J Clin Endocrinol Metab, 70, 817-818, 1990 CLO,SEQ,EXP,LOC,CYG "Brinkman A &: EMBO J, 7, N8, 2417-2423, 1988 LOC,FAG "Ehrenborg E &: Genomics, 12, 497-502, 1992 LOC "Ekstrand J &: Genomics, 6, 413-418, 1990 FUN,MEB "Forbes &: BBRC, 157, N1, 196-202, 1989 CLO,PRO "Julkunen M &: FEBS Lett, 236, 295-302, 1988 |
SWI | SWISSPROT: P08833 |
KEY | sex, trp, horm |
CLA | coding, basic |
LOC | 07 p13-12 |
MIM | MIM: 146730 |
SYN | IGFBP1 IBP1 |
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